Protein Alignment Hsp60D and CCT6A

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001753.1
• Gene: CCT6A / 908
• HGNCID: 1620
• Length: 531
• Species: Homo sapiens
• Alignment Length: 576
• Identity: 130/576 - (22%)
• Similarity: 222/576 - (38%)
• Gaps: 135/576 - (23%)

  Fly    26 ARCLLMQGVNV-----LANAVATTLGPKGRNVLIEQLLISP----RITKDGITVANNVQLGNRRQ 81
            ||......||:     |.:.:.|.|||||    ..::|:|.    ::||||..:.:.:|:    |
Human    14 ARAQAALAVNISAARGLQDVLRTNLGPKG----TMKMLVSGAGDIKLTKDGNVLLHEMQI----Q 70

  Fly    82 DMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNV------QLLREGILEGSR 140
            .....|:.:.....::..||| ||:.:|..|      .:|:|:.:.:      :::.||......
Human    71 HPTASLIAKVATAQDDITGDG-TTSNVLIIG------ELLKQADLYISEGLHPRIITEGFEAAKE 128

  Fly   141 AVCDALGE--MSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESHSPFD--- 200
            .....|.|  :|:.:|....:: ||:.:|..... ||| .|::.|.....::.:|:...|.|
Human   129 KALQFLEEVKVSREMDRETLID-VARTSLRTKVH-AEL-ADVLTEAVVDSILAIKKQDEPIDLFM 190

  Fly   201 ------------EAKIQEGITIASGYYSPFFAKQSHTLELENCLLLLTLAKI------------- 240
                        :..:..|:.:..|...|...|:.....:..|.:.|...|.
Human   191 IEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYEKTEVNSGFFYKSAEE 255

  Fly   241 -------------DQVEQILPALELARL----KERPLLIIAKNFGSDLLKILVLNNLQGRVQVCA 288
                         |:|::|   :||.|.    .::..::|.:. |.|...:..|:. :|.|.:..
Human   256 REKLVKAERKFIEDRVKKI---IELKRKVCGDSDKGFVVINQK-GIDPFSLDALSK-EGIVALRR 315

  Fly   289 VKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQ 353
            .|.        ..||.:..|.||..|   :|..|||.:.||          ...|:....:.||:
Human   316 AKR--------RNMERLTLACGGVAL---NSFDDLSPDCLG----------HAGLVYEYTLGEEK 359

  Fly   354 VQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVA 418
                           ||.:|    |....|    ..|:.:.|.::..:::.||...|.|.||:.|
Human   360 ---------------FTFIE----KCNNPR----SVTLLIKGPNKHTLTQIKDAVRDGLRAVKNA 401

  Fly   419 ISDG-VVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLPCYTIARNAGVDPNEVLRRV 482
            |.|| ||||.|...:.....|.:..|:.....|:|.:...|||.:....:|:|:|.|..|.|.::
Human   402 IDDGCVVPGAGAVEVAMAEALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKI 466

  Fly   483 L---KGSGN-YGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIA-SLLATTEVL 533
            .   ..||. .|.|...||.......|:.|...|.:..:.|...|| ::|...|::
Human   467 QAEHSESGQLVGVDLNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	130/576 (23%)
		GroEL	18..536	CDD:239460	130/576 (23%)
CCT6A	NP_001753.1	chap_CCT_zeta	3..530	CDD:274088	130/576 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810