Protein Alignment Hsp60D and CCT5

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_012598.1
• Gene: CCT5 / 853527
• SGDID: S000003825
• Length: 562
• Species: Saccharomyces cerevisiae
• Alignment Length: 572
• Identity: 136/572 - (23%)
• Similarity: 227/572 - (39%)
• Gaps: 169/572 - (29%)

  Fly    23 GAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISP----RITKDGITVANNVQLGNRRQDM 83
            |.||:...:.....:|:.:.|:|||:|    ::::||||    .||.||.|:.:.::|.|..
Yeast    43 GLEAKKSHILAARSVASIIKTSLGPRG----LDKILISPDGEITITNDGATILSQMELDNEI--- 100

  Fly    84 GVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQ------------------------- 123
             .:||.|.:.:.::::|||||...:||..:..|.:.::::
Yeast   101 -AKLLVQLSKSQDDEIGDGTTGVVVLASALLDQALELIQKGIHPIKIANGFDEAAKLAISKLEET 164

  Fly   124 ----SKVNVQLLREGILEGSRAVCDALGE--MSQSVDTIGQ--VEAVAKVALNGDER-----LAE 175
                |..|.:|.|:.:|   ||...:||.  :|:..|...:  ||||..| ::.|.:     |.:
Yeast   165 CDDISASNDELFRDFLL---RAAKTSLGSKIVSKDHDRFAEMAVEAVINV-MDKDRKDVDFDLIK 225

  Fly   176 LIGDIILELGDS----GVILLKE-SHSPFDEAKI-QEG-----ITIASGYYSPFFAKQSHTLELE 229
            :.|.:...:.||    ||||.|: ||....:..: :||     :.|.:..:.|...|..|.|:
Yeast   226 MQGRVGGSISDSKLINGVILDKDFSHPQMPKCVLPKEGSDGVKLAILTCPFEPPKPKTKHKLD-- 288

  Fly   230 NCLLLLTLAKIDQVE--QILPALELARLKERPLLIIAKNFGSDLL-----------KILVLNNLQ 281
                      |..||  |.|...|..:.||  ::...|..|:|::           .:|:.|:|
Yeast   289 ----------ISSVEEYQKLQTYEQDKFKE--MIDDVKKAGADVVICQWGFDDEANHLLLQNDL- 340

  Fly   282 GRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQP 346
                      |:......:|:|.||.:|.|.::   ....|||::.||......
Yeast   341 ----------PAVRWVGGQELEHIAISTNGRIV---PRFQDLSKDKLGTCSRIY----------- 381

  Fly   347 INVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDA 411
                 ||.....:|...:|:::      ...||         .|.||.|::::.|.|.:...:|:
Yeast   382 -----EQEFGTTKDRMLIIEQS------KETKT---------VTCFVRGSNKMIVDEAERALHDS 426

  Fly   412 LHAVRVAISDG-VVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVK-------------DALRL 462
            |..||..:.|. ||.|||.|.:             .|.|.|..|..|             .||..
Yeast   427 LCVVRNLVKDSRVVYGGGAAEV-------------TMSLAVSEEADKQRGIDQYAFRGFAQALDT 478

  Fly   463 PCYTIARNAGVDPNEVL-----RRVLKGSGNYGYDAAAGEFGDLVVRGIVDP 509
            ...|:|.|:|:||...|     :::.:...|.|.|.......|:....:|||
Yeast   479 IPMTLAENSGLDPIGTLSTLKSKQLKEKISNIGVDCLGYGSNDMKELFVVDP 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	136/572 (24%)
		GroEL	18..536	CDD:239460	136/572 (24%)
CCT5	NP_012598.1	TCP1_epsilon	23..555	CDD:239455	136/572 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810