Protein Alignment Hsp60D and TCP1

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_010498.1
• Gene: TCP1 / 851798
• SGDID: S000002620
• Length: 559
• Species: Saccharomyces cerevisiae
• Alignment Length: 620
• Identity: 141/620 - (22%)
• Similarity: 251/620 - (40%)
• Gaps: 146/620 - (23%)

  Fly     2 LSRLGRSGRA------GVRTFANDIRFGAEARCLLMQGVNVL-----ANAVATTLGPKGRNVLIE 55
            :|:|..:.|:      |.:...:|||           ..|||     ||.|.::|||.|    ::
Yeast     1 MSQLFNNSRSDTLFLGGEKISGDDIR-----------NQNVLATMAVANVVKSSLGPVG----LD 50

  Fly    56 QLLISP----RITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQ 116
            ::|:..    .:|.||.|:.:.:.:.:....:.|:|.:|    .:.::|||||:..|:|..:..:
Yeast    51 KMLVDDIGDFTVTNDGATILSLLDVQHPAGKILVELAQQ----QDREIGDGTTSVVIIASELLKR 111

  Fly   117 GMHVLRQSKVNVQLLREGILEGSRAVCDALGE-MSQSVDTIGQ--VEAVAKVALNG------DER 172
            ...::: :|::...:..|.....|.....:.| :|.||||:|:  :..:||.:::.      .:.
Yeast   112 ANELVK-NKIHPTTIITGFRVALREAIRFINEVLSTSVDTLGKETLINIAKTSMSSKIIGADSDF 175

  Fly   173 LAELIGDIILEL------GD-----SGVILLKESHSPFDEAKIQEGITIASGYYSPFFAKQSHTL 226
            .:.::.|.:|.:      |:     ..|.:||.......|:.:..|..:.....|....|:....
Yeast   176 FSNMVVDALLAVKTQNSKGEIKYPVKAVNVLKAHGKSATESLLVPGYALNCTVASQAMPKRIAGG 240

  Fly   227 ELENCLLLLTLAK----------IDQVEQILPALELARLKERPLLIIAKNFGSDLLKIL-----V 276
            .::...|.|.|.|          ||..||    ||..|.:|..:::      ..:.||:     |
Yeast   241 NVKIACLDLNLQKARMAMGVQINIDDPEQ----LEQIRKREAGIVL------ERVKKIIDAGAQV 295

  Fly   277 LNNLQGRVQVCA---VKAPSFGDEQC--EEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVV 336
            :...:|...:|.   |:|...|..:|  |::..||.|||..|:...|:|
Yeast   296 VLTTKGIDDLCLKEFVEAKIMGVRRCKKEDLRRIARATGATLVSSMSNL---------------- 344

  Fly   337 DAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEV 401
            :.:||.....:.:.:|.||.:           |:|.|...:|   |..:...::|.:.|.::..:
Yeast   345 EGEETFESSYLGLCDEVVQAK-----------FSDDECILIK---GTSKHSSSSIILRGANDYSL 395

  Fly   402 SERKDRFNDALHAVRVAISDG-VVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLPCY 465
            .|.:...:|:|..|:..:..| ||||||.........||....|.....|:.......||.:...
Yeast   396 DEMERSLHDSLSVVKRTLESGNVVPGGGCVEAALNIYLDNFATTVGSREQLAIAEFAAALLIIPK 460

  Fly   466 TIARNAGVD-------------------PNEVLRRVLKGSGNYGYDAAAGEFGDLVVRGIVDPT- 510
            |:|.||..|                   |.:|.||..:   |||.|...|:..|.:..|:::||
Yeast   461 TLAVNAAKDSSELVAKLRSYHAASQMAKPEDVKRRSYR---NYGLDLIRGKIVDEIHAGVLEPTI 522

  Fly   511 ---KVLQSAMTSAAGIASLLATTEVLITKQPTKPK 542
               |.|:||:.:...|..:    :.:||..|..||
Yeast   523 SKVKSLKSALEACVAILRI----DTMITVDPEPPK 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	137/603 (23%)
		GroEL	18..536	CDD:239460	133/590 (23%)
TCP1	NP_010498.1	TCP1_alpha	17..549	CDD:239451	135/598 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810