Protein Alignment Hsp60D and Bbs10

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_082190.1
• Gene: Bbs10 / 71769
• MGIID: 1919019
• Length: 713
• Species: Mus musculus
• Alignment Length: 645
• Identity: 122/645 - (18%)
• Similarity: 229/645 - (35%)
• Gaps: 173/645 - (26%)

  Fly     3 SRLGRSGRAGVRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDG 67
            |.|.::| .|.:||   |.|    .|.|::|::        .:|.||               ||.
Mouse    70 SHLKKTG-DGAKTF---IIF----LCHLLRGLH--------AIGEKG---------------KDS 103

  Fly    68 ITVANNVQLGNRRQDMGVQ--LLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQL 130
            .| :.|:|...|......|  .:.||......:     |...|:.|.::...:.|...|....:|
Mouse   104 FT-SENIQSHERHWKNCCQWKSISQALQTFQTQ-----TLGCIVDRSLSRHYLSVFSSSTEGRKL 162

  Fly   131 LR---EGILEGSRAVCDALGEMSQSVDTIGQVEAVAK-VALNGDERLAELIGDIILEL--GDSGV 189
            .|   |.:||.  ..|..:|..:....:....:.|.| :|......:.||:.....||  |.:|:
Mouse   163 CRHSLELLLEA--YFCGRVGRNNHRFISQLMCDYVFKCMACESGVEVFELLDHCFAELNVGVTGL 225

  Fly   190 ILLKESHSPFDEAKIQEGITIASGY--YSPFFAKQSHTLELENCLLLLTLAKIDQVEQILPALEL 252
                    |..:::|.:|:.:...:  |.|          .:..:.::.:.:|.|.:......|.
Mouse   226 --------PVSDSRIIDGLVLPRDFSMYCP----------ADGDIRMVIVTEILQPQFSSAGSEF 272

  Fly   253 ARLKERPLLIIAKNFGSDLLKILVLNNLQG---RVQVCAVKAP----------SFGDEQCEEMED 304
            . |........::.:.:|..| .|:|:|:|   ::.:.:||.|          |....:|...|:
Mouse   273 V-LNSETQFQASQCWITDRTK-TVMNHLRGQNVKLLLTSVKQPDLVIYCARLNSISVVECLSAEE 335

  Fly   305 IAFA---TG--GHLLEDASSLADLSEEDLGEVMEAVV--DAKETH---------------LLQPI 347
            ::..   ||  ..:|.:.:|..::|:..|.:..:.::  ..:..|               |..|:
Mouse   336 VSLVQRITGLSPCVLPEVASQCEISDSTLVKFCKPLILRSKRYVHLGLISTCAFIPHSMVLCGPV 400

  Fly   348 NVNEEQVQCRIQDIRELIDEAFTDVELDR-LKTRLGRLQGHLATIFVGGTSELEVSERKDRFND- 410
            ....||.:.......:::.:.|||::|:. ::|   :.|.:.:.:....:.|...|...|::.|
Mouse   401 LGLVEQHERAFHGAFKMLRQLFTDLDLNYIIQT---KQQCNPSPLAYDNSRERNHSPETDKYQDI 462

  Fly   411 ------------------ALHAVRVAISDG----------VVPGGGTAYLRCIP-----VLDELP 442
                              .|.|....:..|          :.|......|:|:|     ::|...
Mouse   463 VAKSKNKLETQTHLEVYSGLGASDTELRAGKPWSAHKKTPIAPSQTDEMLKCLPPERSGIIDNCD 527

  Fly   443 ----------PTDIMELQVGREIVKDALRLPCYTIARNAGVDPN-EVLRRVLKGSGNYGYDAA-- 494
                      ||   ....|.||..:.|:     ::.|||.... .|:|:.|......||.::
Mouse   528 LSIENHSTGNPT---AEDTGTEISFEHLQ-----VSDNAGKGYTLPVMRKSLDTCTCQGYCSSTV 584

  Fly   495 --------AGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLITKQPTKPKIPKN 546
                    .|.|..|:...::...|  |...:....|:.|:|...:.|.|...|||..|:
Mouse   585 PAGCVLPVGGSFEILMSYYLLSYAK--QCRQSDETVISMLIADALLGIPKILYKPKKGKD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	117/633 (18%)
		GroEL	18..536	CDD:239460	111/618 (18%)
Bbs10	NP_082190.1	chaperonin_like	7..>111	CDD:295468	18/72 (25%)
		Cpn60_TCP1	13..>424	CDD:278544	77/412 (19%)
		CNH	111..>209	CDD:295303	19/104 (18%)
		chaperonin_like	<587..695	CDD:295468	14/58 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900