Protein Alignment Hsp60D and TCP1

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_110379.2
• Gene: TCP1 / 6950
• HGNCID: 11655
• Length: 556
• Species: Homo sapiens
• Alignment Length: 583
• Identity: 128/583 - (21%)
• Similarity: 232/583 - (39%)
• Gaps: 136/583 - (23%)

  Fly    22 FGAEARCLLMQGVNV-----LANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQ 81
            ||..:....::..||     :||.|.::|||.|.:.::...:....||.||.|:...:::    :
Human     8 FGDRSTGETIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEV----E 68

  Fly    82 DMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVC-DA 145
            ....::|.:..:..:.:||||||:..|:|..:......:::|     ::....::.|.|..| :|
Human    69 HPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQ-----KIHPTSVISGYRLACKEA 128

  Fly   146 LGEMSQSV----DTIGQ---VEAVAK-------VALNGDERLAELIGDIILELGDSGV------- 189
            :..:::::    |.:|:   :.| ||       :.:||| ..|.::.|.:|.:..:.:
Human   129 VRYINENLIVNTDELGRDCLINA-AKTSMSSKIIGINGD-FFANMVVDAVLAIKYTDIRGQPRYP 191

  Fly   190 ---ILLKESHSPFDEAKIQEGITIASGYYSPF--------------------FAKQSHTLELENC 231
               :.:.::|     .:.|....:.|||....                    |:.|...::|...
Human   192 VNSVNILKAH-----GRSQMESMLISGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQ 251

  Fly   232 LLLLTLAKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGD 296
            :::....|:||:.|    .|....|||...|:|.  |:::  ||....:........|:|.:...
Human   252 VVITDPEKLDQIRQ----RESDITKERIQKILAT--GANV--ILTTGGIDDMCLKYFVEAGAMAV 308

  Fly   297 EQC--EEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQ 359
            .:.  .:::.||.|:|..:|   |:||:|..|   |..||.:                     :.
Human   309 RRVLKRDLKRIAKASGATIL---STLANLEGE---ETFEAAM---------------------LG 346

  Fly   360 DIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAV-RVAISDGV 423
            ...|::.|...|.||..:|....|..   |:|.:.|.::....|.:...:|||..| ||..|..|
Human   347 QAEEVVQERICDDELILIKNTKARTS---ASIILRGANDFMCDEMERSLHDALCVVKRVLESKSV 408

  Fly   424 VPGGGTAYLRCIPVLDELPPTDIMELQVG-REIVKDALRLPCYTIARNAGVDPNEVL-------- 479
            |||||.........|:....:.....|:. .|..:..|.:| .|:|.||..|..:::
Human   409 VPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIP-NTLAVNAAQDSTDLVAKLRAFHN 472

  Fly   480 -------RRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLIT 535
                   |:.||.   .|.|.:.|:..|....|:.:||.|         .:.||...||..||
Human   473 EAQVNPERKNLKW---IGLDLSNGKPRDNKQAGVFEPTIV---------KVKSLKFATEAAIT 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	128/583 (22%)
		GroEL	18..536	CDD:239460	128/583 (22%)
TCP1	NP_110379.2	TCP1_alpha	9..535	CDD:239451	127/582 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810