Protein Alignment Hsp60D and Hspd1

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_071565.2
• Gene: Hspd1 / 63868
• RGDID: 621314
• Length: 573
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 226/536 - (42%)
• Similarity: 354/536 - (66%)
• Gaps: 8/536 - (1%)

  Fly    14 RTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGN 78
            |.:|.|::|||:||.|::|||::||:|||.|:|||||.|:|||...||::||||:|||.::.|.:
  Rat    24 RAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88

  Fly    79 RRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVC 143
            :.:::|.:|::...||||.:.||||||||:|||.||.:|...:.:....|: :|.|::....||.
  Rat    89 KYKNIGAKLVQDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVE-IRRGVMLAVDAVI 152

  Fly   144 DALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESHSPFDEAKIQEGI 208
            ..|.:.|:.|.|..::..||.::.|||:.:..:|.|.:.::|..|||.:|:..:..||.:|.||:
  Rat   153 AELKKQSKPVTTPEEIAQVATISANGDKDIGNIISDAMKKVGRKGVITVKDGKTLNDELEIIEGM 217

  Fly   209 TIASGYYSPFFAKQS--HTLELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAKNFGSDL 271
            ....||.||:|...|  ...|.::..:||:..||..|:.|:||||:|....:||:|||::...:.
  Rat   218 KFDRGYISPYFINTSKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANAHRKPLVIIAEDVDGEA 282

  Fly   272 LKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDAS---SLADLSEEDLGEVME 333
            |..||||.|:..:||.|||||.|||.:..:::|:|.||||.:..:..   :|.|:...|||:|.|
  Rat   283 LSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLKDMAIATGGAVFGEEGLNLNLEDVQAHDLGKVGE 347

  Fly   334 AVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSE 398
            .:|...:..||:. ..::..::.|||:|.|.:|...::.|.::|..||.:|...:|.:.|||||:
  Rat   348 VIVTKDDAMLLKG-KGDKAHIEKRIQEITEQLDITTSEYEKEKLNERLAKLSDGVAVLKVGGTSD 411

  Fly   399 LEVSERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLP 463
            :||:|:|||..|||:|.|.|:.:|:|.|||.|.|||||.||.|.|.: .:.::|.||:|.||::|
  Rat   412 VEVNEKKDRVTDALNATRAAVEEGIVLGGGCALLRCIPALDSLKPAN-EDQKIGIEIIKRALKIP 475

  Fly   464 CYTIARNAGVDPNEVLRRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLA 528
            ..|||:||||:.:.::.::|:.|...||||..|:|.::|.:||:|||||:::|:..|||:||||.
  Rat   476 AMTIAKNAGVEGSLIVEKILQSSSEVGYDAMLGDFVNMVEKGIIDPTKVVRTALLDAAGVASLLT 540

  Fly   529 TTEVLITKQPTKPKIP 544
            |.|.::|:.|.:.|.|
  Rat   541 TAEAVVTEIPKEEKDP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	220/522 (42%)
Hspd1	NP_071565.2	GroEL	28..548	CDD:239460	220/522 (42%)