Protein Alignment Hsp60D and Bbs10

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001102756.1
• Gene: Bbs10 / 500832
• RGDID: 1560748
• Length: 713
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 103/574 - (17%)
• Similarity: 183/574 - (31%)
• Gaps: 201/574 - (35%)

  Fly    36 VLANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNNKVG 100
            ||.......:||:|..||..:......:::||..:...:.|    :....:::....::...|.|
  Rat    16 VLETIANRCVGPEGGLVLCTKPTGEVLLSRDGGCLLEALHL----EHPLARMIVACVSSHLKKTG 76

  Fly   101 DGTTTATI----LARGI-------------------------ACQGMHVLR-----QSK-----V 126
            ||..|..|    |.||:                         .||...:.|     |::     |
  Rat    77 DGAKTFIIFLCHLLRGLHAIGEKEKDSFTSEDIQSHERHWKNCCQWKSISRALLRFQTQTLGCIV 141

  Fly   127 NVQLLREGI------LEGSRAVCDALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDII---- 181
            :..|.|..:      .|| |.:|      .:|::.:.:.....:|..|....:::|:.|.:
  Rat   142 DQHLSRHYLSAFSSSAEG-RTLC------RRSLELLLEPYFCGRVGRNNHRFISQLMCDYVFKCM 199

  Fly   182 ------------------LELGDSGVILLKESHSPFDEAKIQEGITIASGY--YSPFFAKQSHTL 226
                              |.:|.:|:        |..|::|.:|:.:...:  |.|........:
  Rat   200 ACESGIEVFEFLDNCFVELNVGVTGL--------PVSESRIVDGLVLPRDFSVYCPADGGIRMVI 256

  Fly   227 ELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQG---RVQVCA 288
            ..|   :|..|......|.:|.:....:..:..::...|.         |:|:|:.   ::.:.:
  Rat   257 VTE---ILQPLFSSSSSEFVLDSETQFQASQSWIMDRTKT---------VMNHLRSHNVKLLLSS 309

  Fly   289 VKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQ 353
            ||.|.. ...|..:..|            |.:..||.|::..|.....       |.|..:.|..
  Rat   310 VKQPDL-VTYCARLNSI------------SVVECLSSEEVSLVQRITG-------LSPCVLPELA 354

  Fly   354 VQCRIQD------IRELIDEAFTDVELDRLKTRLGRLQGHLATI----FV-------GGTSELEV 401
            .||.|.|      .:.||             .|.|| ..||..:    ||       |....| |
  Rat   355 SQCHIADSALVRFCKPLI-------------VRSGR-YAHLGLVSTCAFVPHCVVLCGPVLGL-V 404

  Fly   402 SERKDRFNDALHAVRVAISDGVVPGGGTAYLRCI----------PVLD-------ELPPT----- 444
            .:.:..|:.|...:|...:|        ..|.|:          |:.|       ..|.|
  Rat   405 QQHESAFHGAFKMLRQLFTD--------LDLNCMIQTKERRNPSPLADSSNRESSHSPKTGKYQD 461

  Fly   445 ------DIMELQVGREI-----VKDALRLPC--YTIARNAGVDP---NEVLRRV 482
                  |.:|.|...|:     ..|...:.|  ::..:...:||   ||:.:|:
  Rat   462 VVAKNKDKLETQTRLEVYPRLGASDTELITCKLWSAHKETSIDPSQTNEIPKRL 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	103/574 (18%)
Bbs10	NP_001102756.1	Cpn60_TCP1	13..>424	CDD:395068	85/473 (18%)