Protein Alignment Hsp60D and Hsp60B

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_524925.1
• Gene: Hsp60B / 48572
• FlyBaseID: FBgn0011244
• Length: 648
• Species: Drosophila melanogaster
• Alignment Length: 536
• Identity: 240/536 - (44%)
• Similarity: 354/536 - (66%)
• Gaps: 13/536 - (2%)

  Fly     8 SGRAGVRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDGITVAN 72
            |.|...|.::.|:|||:..|.::::||::||:|||.|:|||||:|::|:...||:|||||.|||.
  Fly    12 SSRCFARMYSKDVRFGSGVRAMMIRGVDILADAVAVTMGPKGRSVIVERPWTSPKITKDGFTVAR 76

  Fly    73 NVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILE 137
            ::.|.::..::|.:|::...:|||...||||||||:|||.||.:|.:.:......|: :|.|::.
  Fly    77 SIALKDQHMNLGAKLVQDVADNTNESAGDGTTTATVLARAIAKEGFNQITMGANPVE-IRRGVML 140

  Fly   138 GSRAVCDALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESHSPFDEA 202
            ....|.|.|.|||::|:|..:::.||.::.|||..:..|||:...::|..|.|.:|:.....||.
  Fly   141 AVDVVKDKLKEMSKAVETREEIQQVATLSANGDTEIGRLIGEATDKVGPRGTITVKDGKRLKDEL 205

  Fly   203 KIQEGITIASGYYSPFFAKQS--HTLELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAK 265
            .|.:|:...:||.||||...|  ..:|..|.|::::|.||..:.||:..||.:..:.|||:|||:
  Fly   206 NIIQGLRFDNGYVSPFFVNSSKGSKVEFANALVMISLKKITGLSQIVKGLEQSLRQRRPLIIIAE 270

  Fly   266 NFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSE---ED 327
            :...:.|..||||.|:..:||||||:||:|..:.|.:.||:.|||..:..|..:.:.:.|   ||
  Fly   271 DISGEALNALVLNKLRLGLQVCAVKSPSYGHHRKELIGDISAATGATIFGDDINYSKMEEAKLED 335

  Fly   328 LGEVMEAVVDAKETHLLQ---PINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLA 389
            ||:|.|||:....|.|||   ...:.|.::| :|||  ||.::.....:.|||:.||..|...:|
  Fly   336 LGQVGEAVISKDSTMLLQGKPKTGLLEMRIQ-QIQD--ELAEKQIKPEQRDRLRQRLSALTKGVA 397

  Fly   390 TIFVGGTSELEVSERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQVGRE 454
            .:.:||.||:||:|:|||..|||:|.|.||.:|:|||||||:|||||.|.|| .|:..:||.|.:
  Fly   398 VLHIGGGSEVEVNEKKDRVVDALNATRAAIEEGIVPGGGTAFLRCIPYLQEL-KTESADLQKGVD 461

  Fly   455 IVKDALRLPCYTIARNAGVDPNEVLRRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTS 519
            ||.:|||:||.|||:|||||...|:.:||.||.:|||||...|:..||.:||:||||||::|:|.
  Fly   462 IVCNALRMPCQTIAQNAGVDGPMVVAKVLNGSEDYGYDAMGDEYCRLVEKGIIDPTKVLRTAITD 526

  Fly   520 AAGIASLLATTEVLIT 535
            |||:||||:||||:||
  Fly   527 AAGVASLLSTTEVVIT 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	237/526 (45%)
Hsp60B	NP_524925.1	GroEL	22..543	CDD:239460	237/526 (45%)