Protein Alignment Hsp60D and cct5

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_997778.1
• Gene: cct5 / 322258
• ZFINID: ZDB-GENE-030131-977
• Length: 541
• Species: Danio rerio
• Alignment Length: 586
• Identity: 121/586 - (20%)
• Similarity: 233/586 - (39%)
• Gaps: 141/586 - (24%)

  Fly    23 GAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISP----RITKDGITVANNVQLGNRRQDM 83
            |.||....:.....:||.:.|:|||.|    ::::::..    .:|.||.|:.:.:.:.::...:
Zfish    30 GLEALKSHILAAKAVANTLRTSLGPNG----LDKMMVDKDGEVTVTNDGATILSMMDVDHQIAKL 90

  Fly    84 GVQLLRQATNNTNNKVGDGTTTATILARGIACQ-------GMHVLRQSKVNVQLLREGILEGSRA 141
            .|:|    :.:.::::|||||...:||..:..|       |:|.:|        :.:|..:.::.
Zfish    91 MVEL----SKSQDDEIGDGTTGVVVLAGALLEQAEQLLDRGIHPIR--------IADGYDQAAKI 143

  Fly   142 VCDALGEMSQS--VD-------------TIGQV------EAVAKVALNG------------DERL 173
            ..:.|.::..|  ||             |:|..      ..:|::|:|.            |..|
Zfish   144 AIEQLDKIGDSFPVDPNNTESLVQTAMTTLGSKVINRCHRQMAEIAVNAILTVADMERKDVDFEL 208

  Fly   174 AELIGDIILELGDS----GVILLKE-SHSPFDEAKIQEGITIASGYYSPFFAKQSHTLELENCLL 233
            .::.|.:..:|.|:    |||:.|| ||....:......|.|.:..:.|...|..|.|::.:...
Zfish   209 IKVEGKVGGKLEDTQLIKGVIVDKEFSHPQMPKVLKDTKIAILTCPFEPPKPKTKHKLDVTSVED 273

  Fly   234 LLTLAKI--DQVEQILPALELARLKER--PLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSF 294
            ...|.|.  |:.:::     :.::||.  .|.|....|..:...:|:.|.|..   :..|..|
Zfish   274 YKALQKYEKDKFQEM-----IRQVKENGANLAICQWGFDDEANHLLLQNELPA---IRWVGGP-- 328

  Fly   295 GDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGE---VMEAVVDAKETHLLQPINVNEEQVQC 356
                  |:|.||.||||.::   ....:|:.|.||.   |.|......:..:|    |.||   |
Zfish   329 ------EIELIAIATGGRIV---PRFCELTPEKLGTAGLVKEICFGTTKDRML----VIEE---C 377

  Fly   357 RIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVAISD 421
            :                           .....|||:.|.:::.:.|.|...:|||..:|..:.|
Zfish   378 K---------------------------NSRAVTIFIRGGNKMIIEEAKRALHDALCVIRNLVRD 415

  Fly   422 G-VVPGGGTAYLRCI----PVLDELPPTDIMELQVGREIVKDALRLPCYTIARNAGVDPNEVL-- 479
            . :|.|||.:.:.|.    ...|:.|..:    |.......|||.:....:|.|:|::|.:.:
Zfish   416 NRIVYGGGASEIACALAVNEAADKCPSLE----QYAMRAFADALEVIPMALAENSGLNPIQTMTE 476

  Fly   480 ---RRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLITKQPTKP 541
               |:|.:.:...|.|.......|:..:.:::.....:..::.|..:..::...:.:  :.|.:|
Zfish   477 VRARQVKENNSALGIDCLHLSTNDMKQQHVIETLIGKKQQISLATQVVKMILKIDDI--RGPGEP 539

  Fly   542 K 542
            :
Zfish   540 E 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	119/578 (21%)
cct5	NP_997778.1	TCP1_epsilon	10..535	CDD:239455	119/579 (21%)