Protein Alignment Hsp60D and Hsp60A

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_511115.2
• Gene: Hsp60A / 32045
• FlyBaseID: FBgn0015245
• Length: 573
• Species: Drosophila melanogaster
• Alignment Length: 548
• Identity: 238/548 - (43%)
• Similarity: 365/548 - (66%)
• Gaps: 8/548 - (1%)

  Fly     2 LSRLGRSGRAGVRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKD 66
            |:|...|.:..:|.:|.|:|||.|.|.:::|||:|||:|||.|:|||||||:|||...||:||||
  Fly     8 LARSSISRQLAMRGYAKDVRFGPEVRAMMLQGVDVLADAVAVTMGPKGRNVIIEQSWGSPKITKD 72

  Fly    67 GITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLL 131
            |:|||.:::|.::.|::|.:|::...||||.:.||||||||:|||.||.:|...:.:....|: :
  Fly    73 GVTVAKSIELKDKFQNIGAKLVQDVANNTNEEAGDGTTTATVLARAIAKEGFEKISKGANPVE-I 136

  Fly   132 REGILEGSRAVCDALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESH 196
            |.|::.....|.|.|..||:.|.|..::..||.::.|||:.:..||.:.:.::|..|||.:|:..
  Fly   137 RRGVMLAVETVKDNLKTMSRPVSTPEEIAQVATISANGDQAIGNLISEAMKKVGRDGVITVKDGK 201

  Fly   197 SPFDEAKIQEGITIASGYYSPFFAKQSH--TLELENCLLLLTLAKIDQVEQILPALELARLKERP 259
            :..||.::.||:....||.||:|...|.  .:|.::.||||:..||..|:.|:||||||..:.:|
  Fly   202 TLTDELEVIEGMKFDRGYISPYFINSSKGAKVEFQDALLLLSEKKISSVQSIIPALELANAQRKP 266

  Fly   260 LLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSLA--- 321
            |:|||::...:.|..||:|.|:..:||.|||||.|||.:...:.|:|.|:||.:..|.:.|.
  Fly   267 LVIIAEDIDGEALSTLVVNRLKIGLQVAAVKAPGFGDNRKSTLTDMAIASGGIVFGDDADLVKLE 331

  Fly   322 DLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQG 386
            |:...|||:|.|.|:...:|.||:. ...::.|..|...|::.|::..::.|.::|:.||.||..
  Fly   332 DVKVSDLGQVGEVVITKDDTLLLKG-KGKKDDVLRRANQIKDQIEDTTSEYEKEKLQERLARLAS 395

  Fly   387 HLATIFVGGTSELEVSERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQV 451
            .:|.:.|||:||:||:|:|||.:|||:|.|.|:.:|:|||||||.||||..|:.:..|: .:.::
  Fly   396 GVALLRVGGSSEVEVNEKKDRVHDALNATRAAVEEGIVPGGGTALLRCIEKLEGVETTN-EDQKL 459

  Fly   452 GREIVKDALRLPCYTIARNAGVDPNEVLRRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSA 516
            |.|||:.|||:||.|||:|||||...|:.:|...:|:|||||..||:|:|:.:||:|||||:::|
  Fly   460 GVEIVRRALRMPCMTIAKNAGVDGAMVVAKVENQAGDYGYDALKGEYGNLIEKGIIDPTKVVRTA 524

  Fly   517 MTSAAGIASLLATTEVLITKQPTKPKIP 544
            :|.|:|:||||.|.|.::|:.|.:...|
  Fly   525 ITDASGVASLLTTAEAVVTEIPKEDGAP 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	235/537 (44%)
		GroEL	18..536	CDD:239460	230/522 (44%)
Hsp60A	NP_511115.2	PTZ00114	12..549	CDD:185455	235/539 (44%)
		GroEL	24..544	CDD:239460	230/522 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S222
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D183447at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45633
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.800