Protein Alignment Hsp60D and Cct2

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_038934664.1
• Gene: Cct2 / 299809
• RGDID: 1359143
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 138/619 - (22%)
• Similarity: 247/619 - (39%)
• Gaps: 146/619 - (23%)

  Fly     2 LSRLGRSGRAGVRTFA------------NDIRFGAE------ARCLLMQGVNVLANAVATTLGPK 48
            |::|...|..|.|..:            |..:.||:      ||.....|...:.:.|.:|||||
  Rat     8 LTKLSAWGWKGERALSQHLFASLSLAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPK 72

  Fly    49 GRNVLIEQLLISP------RITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTAT 107
            |    ::::|:|.      .:|.||.|:..|:.:.|....:.|.:.|.    .:::||||||:.|
  Rat    73 G----MDKILLSSGRDASLMVTNDGATILKNIGVDNPAAKVLVDMSRV----QDDEVGDGTTSVT 129

  Fly   108 ILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVCDALGEMSQSVD-------------TIGQV 159
            :||..:..:...::.: |::.|.:..|..|.::|..:||  :|.:||             .|...
  Rat   130 VLAAELLREAESLIAK-KIHPQTIIAGWREATKAAREAL--LSSAVDHGSDEVKFWQDLMNIAGT 191

  Fly   160 EAVAKVALNGDERLAELIGDIILELGDSG----VILLKESHSPFDEAKIQEGITIAS--GYYSPF 218
            ...:|:..:..:...:|..:.:|.|..||    :.::|:......::.:.||..:..  |...|
  Rat   192 TLSSKLLTHHKDHFTKLAVEAVLRLKGSGNLEAIHVIKKLGGSLADSYLDEGFLLDKKIGVNQP- 255

  Fly   219 FAKQSHTLELENCLLLL--------------------TLAKIDQVEQILPALELARLKERPLLII 263
                   ..:||..:|:                    :.||:.::|.    .|..::||:...|:
  Rat   256 -------KRIENAKILIANTGMDTDKIKIFGSRVRVDSTAKVAEIEH----AEKEKMKEKVERIL 309

  Fly   264 AKNFGSDLLKILVLN---NLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSE 325
            .......:.:.|:.|   .|.|...|.|::...|..     :|.:|..|||.:    :|..|..|
  Rat   310 KHGINCFINRQLIYNYPEQLFGAAGVMAIEHADFAG-----VERLALVTGGEI----ASTFDHPE 365

  Fly   326 EDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLAT 390
                     :|......|::.:.:.|:          :||.  |:.|.|           |...|
  Rat   366 ---------LVKLGSCKLIEEVMIGED----------KLIH--FSGVAL-----------GEACT 398

  Fly   391 IFVGGTSELEVSERKDRFNDALHAVRVAISD-GVVPGGGTAYLRCIPVLDELPPTDIMELQVGRE 454
            |.:.|.::..:.|.:...:|||..:...:.| ..|.|||     |..:|.....|.:.....|:|
  Rat   399 IVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGG-----CSEMLMAHAVTMLASRTPGKE 458

  Fly   455 IV-----KDALRLPCYTIARNAGVDPNEVLRRV----LKGSGNYGYDAAAGEFGDLVVRGIVDPT 510
            .|     ..|||:....||.|||.|..:::.::    .:|....|.|...|..||:.|.||.:..
  Rat   459 AVAMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGRITAGLDMKEGSIGDMAVLGITESF 523

  Fly   511 KVLQSAMTSAAGIASLLATTEVLITKQPTKPKIP 544
            :|.:..:.|||..|.::...:.:|...|.| ::|
  Rat   524 QVKRQVLLSAAEAAEVILRVDNIIKAAPRK-RVP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	130/581 (22%)
Cct2	XP_038934664.1	TCP1_beta	37..553	CDD:239452	130/584 (22%)