Protein Alignment Hsp60D and Cct3

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_954522.1
• Gene: Cct3 / 295230
• RGDID: 735038
• Length: 545
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 117/574 - (20%)
• Similarity: 215/574 - (37%)
• Gaps: 135/574 - (23%)

  Fly    31 MQGVNVLANAVATTLGPKGRNVLIEQLLISPR----ITKDGITVANNVQLGNRRQDMGVQLLRQA 91
            :.....:|:.:.|.||||.    :.::|:.|.    :|.||..:...:|:    |....:.:.:.
  Rat    27 INAAKTIADIIRTCLGPKS----MMKMLLDPMGGIVMTNDGNAILREIQV----QHPAAKSMIEI 83

  Fly    92 TNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVCD----ALGEMSQS 152
            :...:.:||||||:..|||..:.....|.|.|     |:....::...|...|    .|.::|..
  Rat    84 SRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQ-----QMHPTVVISAYRMALDDMVSTLKKISTP 143

  Fly   153 VDTIGQ---------------------------VEAVAKVAL--NGDE--------RLAELIGDI 180
            ||...:                           ::||..|..  ||.:        |:.::.|.|
  Rat   144 VDVNNRDMMLNIINSSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEKIPGGI 208

  Fly   181 ILELGDS----GVILLKESHSPFDEAKIQEGITIASGYYSPFFAKQSHT-LEL---ENCLLLLTL 237
            |   .||    ||::.|:...|.....|:....:.......:...:|.| :|:   |:...:|.:
  Rat   209 I---EDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQM 270

  Fly   238 AKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEM 302
            .: :.::|:..  ::.:||  |.::|.:...|||.:..::     |..|.|::.....|.
  Rat   271 EE-EYIQQLCE--DIIQLK--PDVVITEKGISDLAQHYLM-----RANVTAIRRVRKTDN----- 320

  Fly   303 EDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDE 367
            ..||.|.|..::   |...:|.|:|:|                        ....:.:|:::.||
  Rat   321 NRIARACGARIV---SRPEELREDDVG------------------------TGAGLLEIKKIGDE 358

  Fly   368 AFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVR-VAISDGVVPGGGTAY 431
            .||.:...:        .....||.:.|.|:..:||.:....||:...| |.:...:|||||.:.
  Rat   359 YFTFITDCK--------DPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASE 415

  Fly   432 LRCIPVLDELPPTDIMELQVGRE-----IVKDALRLPCYTIARNAGVDPNEVL-----RRVLKGS 486
            :.....|     |:..:...|.|     .|..||.:...|:.:|.|.....:|     :...:..
  Rat   416 MAVAHAL-----TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQENC 475

  Fly   487 GNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLITKQPTK 540
            ..:|.:...|...|:...||.:|..|......:|...|.||...:.:::....|
  Rat   476 ETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	116/568 (20%)
Cct3	NP_954522.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		chap_CCT_gamma	6..529	CDD:274085	116/572 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545		1/4 (25%)