Protein Alignment Hsp60D and hspd1

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_851847.1
• Gene: hspd1 / 282676
• ZFINID: ZDB-GENE-021206-1
• Length: 575
• Species: Danio rerio
• Alignment Length: 534
• Identity: 220/534 - (41%)
• Similarity: 352/534 - (65%)
• Gaps: 8/534 - (1%)

  Fly    14 RTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGN 78
            |.:|.|::|||:||.|::|||::||:|||.|:|||||.|:|||...||::||||:|||.::.|.:
Zfish    24 RAYAKDVKFGADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKD 88

  Fly    79 RRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVC 143
            |.:::|.:|::...||||.:.||||||||:|||.:|.:|...:.:....|: :|.|::.....|.
Zfish    89 RYKNIGAKLVQDVANNTNEEAGDGTTTATVLARAVAKEGFDTISKGANPVE-IRRGVMMAVEEVI 152

  Fly   144 DALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESHSPFDEAKIQEGI 208
            ..|.:.|:.|.|..::..||.::.|||..:..:|.:.:.::|..|||.:|:..:..||.:|.||:
Zfish   153 SELKKNSKPVTTPEEIAQVATISANGDTEVGNIISNAMKKVGRKGVITVKDGKTLHDELEIIEGM 217

  Fly   209 TIASGYYSPFF--AKQSHTLELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAKNFGSDL 271
            ....||.||:|  ..:....|.::..:||:..||..|:.|:||||:|....:||:|:|::...:.
Zfish   218 KFDRGYISPYFINTAKGQKCEFQDAYVLLSEKKISSVQSIVPALEIANQHRKPLVIVAEDVDGEA 282

  Fly   272 LKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDAS---SLADLSEEDLGEVME 333
            |..||||.|:..:||.|||||.|||.:..:::|:|.:|||.:..|.:   :|.|:...|.|:|.|
Zfish   283 LSTLVLNRLKVGLQVVAVKAPGFGDNRKNQLQDMAVSTGGTVFGDEAMGLALEDIQAHDFGKVGE 347

  Fly   334 AVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSE 398
            .:|...:|.||:. ..:...::.|:.:|.|.::...:|.|.::|..||.:|...:|.|.|||||:
Zfish   348 VIVTKDDTMLLKG-RGDASAIEKRVNEIAEQLESTNSDYEKEKLNERLAKLSDGVAVIKVGGTSD 411

  Fly   399 LEVSERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLP 463
            :||:|:|||..|||:|.|.|:.:|:|||||.|.|||||.||.:.|.: .:.::|.:|::.:||:|
Zfish   412 VEVNEKKDRVTDALNATRAAVEEGIVPGGGCALLRCIPALDNIKPAN-ADQKIGIDIIRRSLRIP 475

  Fly   464 CYTIARNAGVDPNEVLRRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLA 528
            ..|||:||||:.:.|:.::|:.|...||||..||:.::|.|||:|||||:::|:..|||:||||:
Zfish   476 AMTIAKNAGVEGSLVVEKILQSSTEIGYDAMNGEYVNMVERGIIDPTKVVRTALLDAAGVASLLS 540

  Fly   529 TTEVLITKQPTKPK 542
            |.|.::|:.|.:.|
Zfish   541 TAEAVVTEIPKEEK 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	215/522 (41%)
hspd1	NP_851847.1	GroEL	28..548	CDD:239460	215/522 (41%)