Protein Alignment Hsp60D and Tcp1

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_036802.1
• Gene: Tcp1 / 24818
• RGDID: 3832
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 578
• Identity: 130/578 - (22%)
• Similarity: 231/578 - (39%)
• Gaps: 126/578 - (21%)

  Fly    22 FGAEARCLLMQGVNV-----LANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQ 81
            ||..:....::..||     :||.|.::|||.|.:.::...:....||.||.|:...:::    :
  Rat     8 FGDRSTGEAIRSQNVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEV----E 68

  Fly    82 DMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVC-DA 145
            ....::|.:..:..:.:||||||:..|:|..:......:::|     ::....::.|.|..| :|
  Rat    69 HPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQ-----KIHPTSVISGYRLACKEA 128

  Fly   146 LGEMSQSV----DTIGQ---VEAVAK-------VALNGDERLAELIGDIILEL------GD---- 186
            :..:::::    |.:|:   :.| ||       :.:||| ..|.::.|.:|.:      |.
  Rat   129 VRYINENLIINTDELGRDCLINA-AKTSMSSKIIGINGD-FFANMVVDAVLAVKYTDIRGQPRYP 191

  Fly   187 -SGVILLKESHSPFDEAKIQEGITI-----ASGYYSPF---------FAKQSHTLELENCLLLLT 236
             :.|.:||.......|:.:..|..:     :.|.....         |:.|...::|...:::..
  Rat   192 VNSVNILKAHGRSQIESMLINGYALNCVVGSQGMLKRIVNAKIACLDFSLQKTKMKLGVQVVITD 256

  Fly   237 LAKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQC-- 299
            ..|:||:.|    .|....|||...|:|.  |:::  ||....:........|:|.:....:.
  Rat   257 PEKLDQIRQ----RESDITKERIQKILAT--GANV--ILTTGGIDDMCLKYFVEAGAMAVRRVLK 313

  Fly   300 EEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIREL 364
            .:::.||.|:|..:|   |:||:|..|   |..||.:                     :....|:
  Rat   314 RDLKRIAKASGASIL---STLANLEGE---ETFEATM---------------------LGQAEEV 351

  Fly   365 IDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAV-RVAISDGVVPGGG 428
            :.|...|.||..:|....|..   |:|.:.|.::....|.:...:|||..| ||..|..||||||
  Rat   352 VQERICDDELILIKNTKARTS---ASIILRGANDFMCDEMERSLHDALCVVKRVLESKSVVPGGG 413

  Fly   429 TAYLRCIPVLDELPPTDIMELQVG-REIVKDALRLPCYTIARNAGVDPNEVL------------- 479
            .........|:....:.....|:. .|..:..|.:| .|:|.||..|..:::
  Rat   414 AVEAALSIYLENYATSMGSREQLAIAEFARSLLVIP-NTLAVNAAQDSTDLVAKLRAFHNEAQVN 477

  Fly   480 --RRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLIT 535
              |:.||.   .|.|...|:..|....|:.:||.|         .:.||...||..||
  Rat   478 PERKNLKW---IGLDLVHGKPRDNKQAGVFEPTIV---------KVKSLKFATEAAIT 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	130/578 (22%)
Tcp1	NP_036802.1	TCP1_alpha	9..535	CDD:239451	129/577 (22%)