Protein Alignment Hsp60D and Tcp1

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_038714.2
• Gene: Tcp1 / 21454
• MGIID: 98535
• Length: 556
• Species: Mus musculus
• Alignment Length: 578
• Identity: 129/578 - (22%)
• Similarity: 230/578 - (39%)
• Gaps: 126/578 - (21%)

  Fly    22 FGAEARCLLMQGVNV-----LANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQ 81
            ||..:....::..||     :||.|.::.||.|.:.::...:....||.||.|:...:::    :
Mouse     8 FGDRSTGEAVRSQNVMAAASIANIVKSSFGPVGLDKMLVDDIGDVTITNDGATILKLLEV----E 68

  Fly    82 DMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVC-DA 145
            ....::|.:..:..:.:||||||:..|:|..:......:::|     ::....::.|.|..| :|
Mouse    69 HPAAKVLCELADLQDKEVGDGTTSVVIIAAELLKNADELVKQ-----KIHPTSVISGYRLACKEA 128

  Fly   146 LGEMSQSV----DTIGQ---VEAVAK-------VALNGDERLAELIGDIILEL------GD---- 186
            :..:::::    |.:|:   :.| ||       :.:||| ..|.::.|.:|.:      |.
Mouse   129 VRYINENLIINTDELGRDCLINA-AKTSMSSKIIGINGD-YFANMVVDAVLAVKYTDARGQPRYP 191

  Fly   187 -SGVILLKESHSPFDEAKIQEGITI-----ASGYYSPF---------FAKQSHTLELENCLLLLT 236
             :.|.:||.......|:.:..|..:     :.|.....         |:.|...::|...:::..
Mouse   192 VNSVNILKAHGRSQIESMLINGYALNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITD 256

  Fly   237 LAKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQC-- 299
            ..|:||:.|    .|....|||...|:|.  |:::  ||....:........|:|.:....:.
Mouse   257 PEKLDQIRQ----RESDITKERIQKILAT--GANV--ILTTGGIDDMYLKYFVEAGAMAVRRVLK 313

  Fly   300 EEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIREL 364
            .:::.:|.|:|..:|   |:||:|..|:..||         |.|.|               ..|:
Mouse   314 RDLKHVAKASGASIL---STLANLEGEETFEV---------TMLGQ---------------AEEV 351

  Fly   365 IDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAV-RVAISDGVVPGGG 428
            :.|...|.||..:|....|..   |:|.:.|.::....|.:...:|||..| ||.....||||||
Mouse   352 VQERICDDELILIKNTKARTS---ASIILRGANDFMCDEMERSLHDALCVVKRVLELKSVVPGGG 413

  Fly   429 TAYLRCIPVLDELPPTDIMELQVG-REIVKDALRLPCYTIARNAGVDPNEVL------------- 479
            .........|:....:.....|:. .|..:..|.:| .|:|.||..|..:::
Mouse   414 AVEAALSIYLENYATSMGSREQLAIAEFARSLLVIP-NTLAVNAAQDSTDLVAKLRAFHNEAQVN 477

  Fly   480 --RRVLKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLIT 535
              |:.||.   .|.|...|:..|....|:.:||.|         .:.||...||..||
Mouse   478 PERKNLKW---IGLDLVHGKPRDNKQAGVFEPTIV---------KVKSLKFATEAAIT 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	129/578 (22%)
Tcp1	NP_038714.2	TCP1_alpha	9..535	CDD:239451	128/577 (22%)