Protein Alignment Hsp60D and hsp-60

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_497429.1
• Gene: hsp-60 / 175316
• WormBaseID: WBGene00002025
• Length: 568
• Species: Caenorhabditis elegans
• Alignment Length: 552
• Identity: 230/552 - (41%)
• Similarity: 349/552 - (63%)
• Gaps: 17/552 - (3%)

  Fly     4 RLGRSG--RAGVRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKD 66
            ||.|.|  .|.||::|.|::||||.|..::.|||:||:||:.|:|||||||:|||...||:||||
 Worm     3 RLARKGLQTAVVRSYAKDVKFGAEGRQAMLVGVNLLADAVSVTMGPKGRNVIIEQSWGSPKITKD 67

  Fly    67 GITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLL 131
            |:|||.::.|.::.|::|.:|::...|..|.:.|||||.||:|||.||.:|...:||.. |...:
 Worm    68 GVTVAKSIDLKDKYQNLGAKLIQDVANKANEEAGDGTTCATVLARAIAKEGFESIRQGG-NAVEI 131

  Fly   132 REGILEGSRAVCDALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILELGDSGVILLKESH 196
            |.|::.....|...|.::|:.|.|..::..||.::.|||..:..||.|.:.::|.:|||.:|:..
 Worm   132 RRGVMNAVEVVVAELKKISKKVTTPEEIAQVATISANGDTVVGNLISDAMKKVGTTGVITVKDGK 196

  Fly   197 SPFDEAKIQEGITIASGYYSPFF--AKQSHTLELENCLLLLTLAKIDQVEQILPALELARLKERP 259
            :..||.::.||:....||.||:|  :.:...:|.|..|:||:..||.||:.|:||||||....||
 Worm   197 TLNDELELIEGMKFDRGYISPYFITSAKGAKVEYEKALVLLSEKKISQVQDIVPALELANKLRRP 261

  Fly   260 LLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSL---A 321
            |:|||::...:.|..||||.|:..:||.|:|||.|||.:...::|:..|||..:..|.|:|   .
 Worm   262 LVIIAEDVDGEALTTLVLNRLKVGLQVVAIKAPGFGDNRKNTLKDMGIATGATIFGDDSNLIKIE 326

  Fly   322 DLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQG 386
            |::..|||||.|..:...:|.||:. ..::.:::.||:.|.:.|:::.:|.|.::|..||.:|..
 Worm   327 DITANDLGEVDEVTITKDDTLLLRG-RGDQTEIEKRIEHITDEIEQSTSDYEKEKLNERLAKLSK 390

  Fly   387 HLATIFVGGTSELEVSERKDRFNDALHAVRVAISDGVVPGGGTAYLRCIPVLDELPPTDIMELQV 451
            .:|.:.:||.||:||.|:|||..|||.|.|.|:.:|:|||||.|.||.:..|......: .:.|:
 Worm   391 GVAVLKIGGGSEVEVGEKKDRVTDALCATRAAVEEGIVPGGGVALLRSLTALKNYKAAN-EDQQI 454

  Fly   452 GREIVKDALRLPCYTIARNAGVDPNEVLRRVLKGSG-NYGYDAAAGEFGDLVVRGIVDPTKVLQS 515
            |..|||.||..|..||.:|||::|:.::..|...|. :|||||..|:|.|:...||:|||||:::
 Worm   455 GVNIVKKALTQPIATIVKNAGLEPSSIIDEVTGNSNTSYGYDALNGKFVDMFEAGIIDPTKVVRT 519

  Fly   516 AMTSAAGIASLLATTEVLITKQPTKPKIPKNQ 547
            |:..|:|:||||||||.::|      :|||.:
 Worm   520 ALQDASGVASLLATTECVVT------EIPKEE 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	218/523 (42%)
hsp-60	NP_497429.1	GroEL	19..540	CDD:239460	219/529 (41%)