Protein Alignment Hsp60D and cct-2

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_741031.1
• Gene: cct-2 / 174421
• WormBaseID: WBGene00000378
• Length: 529
• Species: Caenorhabditis elegans
• Alignment Length: 574
• Identity: 121/574 - (21%)
• Similarity: 236/574 - (41%)
• Gaps: 128/574 - (22%)

  Fly    23 GAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISP--------RITKDGITVANNVQLGNR 79
            |..||.....|...:.:.|.:||||||    ::::|||.        ::|.||.|:..::.:.|
 Worm    16 GESARLSSFVGAIAIGDLVKSTLGPKG----MDKILISGNPESAGGIKVTNDGATILKSIGVDN- 75

  Fly    80 RQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSK--VNVQLLREGILEGSRAV 142
               ...::|...:...:::||||||:.|:||       ..:|::::  ||.::..:.|:.|.|.
 Worm    76 ---PAAKVLVDMSMTQDHEVGDGTTSVTVLA-------AELLKEAEKLVNQRIHPQTIISGYRR- 129

  Fly   143 CDALGEMSQSVD---------------TIGQVEAVAKVALNGDERLAELIGDIILELGDSG---- 188
              |||...:|:.               .|.:....:|:.....|..|:|..|.:|.|..||
 Worm   130 --ALGIAQESLKKSSIESGDNIRDDLLKIARTTLGSKILSQHKEHFAQLAVDAVLRLKGSGNLDA 192

  Fly   189 VILLKESHSPFDEAKIQEGITIAS--GYYSPFFAKQSHTL------ELENCLLLLTLAKIDQVEQ 245
            :.::|:.....:|:.:.||..:..  |.:.|...:::..|      :.:...:..:..::|.|.:
 Worm   193 IQIIKKLGGSMNESYLDEGFLLEKLPGMFQPRRVEKAKILIANTPMDTDKVKVFGSRVRVDGVAK 257

  Fly   246 I--LPALELARLKERPLLIIAKNFGSDLLKILVLN---NLQGRVQVCAVKAPSFGDEQCEEMEDI 305
            :  |.|.|..::||:...|:|.|....:.:.|:.|   .|....:|.|::...|     |.:|.:
 Worm   258 VAELEAAEKLKMKEKVDKILAHNCNVFINRQLIYNYPEQLFADAKVMAIEHADF-----EGIERL 317

  Fly   306 AFATGGHLLE--DASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEA 368
            |...||.::.  |:...|.....|               |::.|.:.|:::      :|
 Worm   318 ALVLGGEIVSTFDSPQTAQFGSCD---------------LIEEIMIGEDRL------LR------ 355

  Fly   369 FTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVAISDG-VVPGGGTAYL 432
            |:.|:|           |...::.:.|.::..:.|.:...:|||..:...:.:. .|.|.|.:
 Worm   356 FSGVKL-----------GEACSVVLRGATQQILDESERSLHDALCVLVTHVKESKTVAGAGAS-- 407

  Fly   433 RCIPVLDELPPTDIMELQVGREIVKDALRLPCY---------TIARNAGVDPNEVLRRV----LK 484
                   |:..:..:.::..:...|:||.:..:         .|..|||:|..|::.|:    ..
 Worm   408 -------EILMSSAIAVEAQKVAGKEALAVEAFGRALAQLPTIICDNAGLDSAELVTRLRAEHAN 465

  Fly   485 GSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLITKQP 538
            |..|.|.|...||..|:...|:::...|....::|||.....:...:.:|...|
 Worm   466 GRHNMGIDIEKGEVADVTKLGVIESYNVKLCMVSSAAEATEQILRVDDIIKAAP 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	120/570 (21%)
cct-2	NP_741031.1	TCP1_beta	6..520	CDD:239452	121/574 (21%)