Protein Alignment Hsp60D and CCT3

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_312164.4
• Gene: CCT3 / 1273209
• VectorBaseID: AGAMI1_003261
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 577
• Identity: 112/577 - (19%)
• Similarity: 219/577 - (37%)
• Gaps: 141/577 - (24%)

  Fly    27 RCLLMQGVN---VLANAVATTLGPKGRNVLIEQLLISPR----ITKDGITVANNVQLGNRRQDMG 84
            |.:.::.:|   .:|:.:.|.|||:.    :.::|:.|.    :|.||..:...:.:    |...
Mosquito    21 RKVQLENINAGKTIADLIRTCLGPQA----MMKMLMDPMGGIVMTNDGNAILREITV----QHPA 77

  Fly    85 VQLLRQATNNTNNKVGDGTTTATILARGIACQGMHVLRQS---KVNVQLLREGI----------- 135
            .:.:.:.....:.:||||||:..:||..:.......|:|.   .|.::..||.:
Mosquito    78 AKSMIEIARTQDEEVGDGTTSVIVLAGEMLAVAEQFLQQQIHPTVIIRAYREALEDMVRILQDEV 142

  Fly   136 -LEGSRAVCDALGEMSQS-VDT--IGQVEAVA-KVALNGDERLAELIGDIILELGDSGVILLKES 195
             :|..|:....|.|:.:| |.|  :|:...:| ::||:..|.::      :.|.|.:.:.:.|.:
Mosquito   143 SIELDRSDKKRLAEVVKSCVGTKFVGRWSDLAVRIALDAVETVS------LTENGRTEIDIKKYA 201

  Fly   196 H------SPFDEAKIQEGITIASGYYSPFFAKQSHTLELENCLLL-------------------- 234
            .      ...|::.:..||.:......|   |....:|....:||
Mosquito   202 KVEKIPGGSIDDSCVLRGIMLNKDVTHP---KMRRYIEKPRIVLLDCPLEYKKGESQTNVEIVGD 263

  Fly   235 LTLAKIDQVEQILPALELARLKE-----RPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSF 294
            ....|:.|:|:    ..:|||.|     :|.::..:...|||.:..::     :..:.|::....
Mosquito   264 QDFTKLLQIEE----EHVARLCEDIIAVKPDVVFTEKGVSDLAQHFLM-----KAGITAIRRLRK 319

  Fly   295 GDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQ 359
            .|.     ..:|.|.|..::   :...:|:|:|:|                        ....:.
Mosquito   320 TDN-----NRLARACGATIV---NRTEELTEKDVG------------------------TGAGLF 352

  Fly   360 DIRELIDEAFTDV-ELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVR-VAISDG 422
            :|:::.||.|..| |.:..|.         .||.:.|.|:..::|.:....||||..| :.:...
Mosquito   353 EIKKMGDEYFCFVTECEDPKA---------CTILLRGASKDVLNETERNLQDALHVARNLMLDPK 408

  Fly   423 VVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLPCYTIARNAGVDPNEVLRRV----- 482
            ::||||...:.....|..      .::|.....|..||.:...|:|:|.|.:....|..:
Mosquito   409 LLPGGGAVEMAVSQALTN------KQIQGPYRAVAQALEIIPRTLAQNCGANTIRTLTALRAKHA 467

  Fly   483 ----LKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLIT 535
                ..|...:|.|...|:..|:..:.|.:|..|......:|...|.||...:.:::
Mosquito   468 SHPAADGPCTWGIDGETGQLVDMKEKNIWEPLSVKLQVYKTAVETAILLLRIDDIVS 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	112/577 (19%)
CCT3	XP_312164.4	chap_CCT_gamma	7..529	CDD:274085	112/577 (19%)