Protein Alignment Hsp60D and CCT5

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_307669.4
• Gene: CCT5 / 1269082
• VectorBaseID: AGAMI1_003337
• Length: 540
• Species: Anopheles gambiae
• Alignment Length: 545
• Identity: 122/545 - (22%)
• Similarity: 214/545 - (39%)
• Gaps: 153/545 - (28%)

  Fly    37 LANAVATTLGPKGRNVLIEQLLIS----PRITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNN 97
            :|:.:.::|||||    ::::::|    ..:|.||.|:   ::|.:...::| :|:.|.:.:.::
Mosquito    45 IASIIRSSLGPKG----LDKMMVSGDGEVTVTNDGATI---MKLMDVDHEIG-KLMVQLSQSQDD 101

  Fly    98 KVGDGTTTATILARGIACQ-------GMHVLRQSKVNVQLLREGILEGSR--AVCDALGEMSQSV 153
            ::|||||...:||..:..|       |:|.:|            |.:|..  |.|..     :.:
Mosquito   102 EIGDGTTGVVVLAGALLEQAESLLDRGIHPIR------------IADGFELAAQCAV-----KHL 149

  Fly   154 DTIG--------QVEAVAKVALN--GDE-------RLAELIGDIILELGD--------------- 186
            |||.        ..|.:.:||:.  |.:       ::||:..|.:|.:.|
Mosquito   150 DTIAHPFPVSRDNKEPLIRVAMTTLGSKIVNKCHRQMAEIAVDAVLTVADLEKKDVNFELIKLEC 214

  Fly   187 ------------SGVILLKE-SHSPFDEAKIQEGITIASGYYSPFFAKQSHTLELENCLLLLTLA 238
                        .||::.|. |||..........:.|.:..:.|...|..|.|::.:......|.
Mosquito   215 KVGGRMEDTCLVKGVVVDKTMSHSQMPTVLKDVKLAILTCPFEPPKPKTKHKLDVTSADDYRKLR 279

  Fly   239 KIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVK---APSFGDEQCE 300
            :.:| |:.|..::..:.....|.|....|..:      .|:|..:.|:.||:   .|
Mosquito   280 EYEQ-EKFLQMVKQVKDAGATLAICQWGFDDE------ANHLLLQQQLPAVRWVGGP-------- 329

  Fly   301 EMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELI 365
            |:|.||.||||.::   ....:||.:.||   .|.|                        :|||.
Mosquito   330 EIELIAIATGGRIV---PRFEELSPDKLG---TAGV------------------------VRELS 364

  Fly   366 DEAFTDVEL---DRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVAISDG-VVPG 426
            .....|..|   |.|.||       ..|:.:.|.:::..:|.|...:|||..||..|.|. :|.|
Mosquito   365 FGTTKDKMLVIEDCLNTR-------AVTVLIRGGNQMVTAEAKRSIHDALCVVRSLIRDSRIVYG 422

  Fly   427 GGTAYLRC-IPVLDELPPTDIMELQVGR--EIVKDALRLPCYTIARNAGVDPNEVL-----RRVL 483
            ||.|.:.| :.|..|......:|....|  .:..:::.|   .:|.|:|:.|.|.|     |:..
Mosquito   423 GGAAEISCSLAVAREADQLSTLEQYAFRAFSVALESIPL---ALAENSGLSPIETLSELKARQGT 484

  Fly   484 KGSGNYGYDAAAGEFGDLVVRGIVD 508
            :.|..:|.|.......|:....:::
Mosquito   485 ENSSTFGVDCMLTGNSDMKEHHVIE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	122/545 (22%)
CCT5	XP_307669.4	None