Protein Alignment Hsp60D and Cct7

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_031664.3
• Gene: Cct7 / 12468
• MGIID: 107184
• Length: 544
• Species: Mus musculus
• Alignment Length: 601
• Identity: 131/601 - (21%)
• Similarity: 231/601 - (38%)
• Gaps: 135/601 - (22%)

  Fly     1 MLSRLGRSGRAGVRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPR--- 62
            :|.:.|.....|:....::|     :.|      .|:|.||.|||||:|    :::|::..|
Mouse     7 ILLKEGTDSSQGIPQLVSNI-----SAC------QVIAEAVRTTLGPRG----MDKLIVDGRGKA 56

  Fly    63 -ITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQ-------GMH 119
             |:.||.|:...:.:.:    ...:.|.....:.:.:||||||:.|:||.....|       |:|
Mouse    57 TISNDGATILKLLDVVH----PAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLH 117

  Fly   120 ---VLRQSKVNVQLLREGILEGSRAVCDALGEMSQSVDTIGQVEAVAKVALN----GDERL--AE 175
               ::|..:...||....|.|.:..|     :....|:....:|..|..||:    ..:::  |:
Mouse   118 PQIIIRAFRTATQLAVNKIKEIAVTV-----KKQDKVEQRKMLEKCAMTALSSKLISQQKVFFAK 177

  Fly   176 LIGDIILELGD----SGVILLKESHSPFDEAKIQEGITI------------ASGYYSPFFAKQSH 224
            ::.|.::.|.:    ..:.:.|......:|:::..|:..            ...|.:|..|..:.
Mouse   178 MVVDAVMMLDELLQLKMIGIKKVQGGALEESQLVAGVAFKKTFSYAGFEMQPKKYKNPKIALLNV 242

  Fly   225 TLELENCLLLLTLAKIDQVEQILPALELARLKERPLLIIAK-NFGSDLLKILVLNNLQGRVQVCA 288
            .|||:        |:.|..|     :.:..:::...::.|: |...|.|:.:    .|...:|..
Mouse   243 ELELK--------AEKDNAE-----IRVHTVEDYQAIVDAEWNILYDKLEKI----HQSGAKVIL 290

  Fly   289 VKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQ 353
            .|.| .||...:...|          .|......:.||||...|.|...:.:|           .
Mouse   291 SKLP-IGDVATQYFAD----------RDMFCAGRVPEEDLKRTMMACGGSIQT-----------S 333

  Fly   354 VQCRIQDIR---ELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAV 415
            |...:.|:.   ::.:|  |.:..:|.....|..:....||.:.|.:|..:.|.:...:||:..|
Mouse   334 VNALVPDVLGHCQVFEE--TQIGGERYNFFTGCPKAKTCTIILRGGAEQFMEETERSLHDAIMIV 396

  Fly   416 RVAI-SDGVVPGGGTA----------YLRCIPVLDELPPTDIMELQVGREIVKDALRLPCYTIAR 469
            |.|| :|.||.|||..          |.|.||        ...:|.:|  ....||.:....:..
Mouse   397 RRAIKNDSVVAGGGAIEMELSKYLRDYSRTIP--------GKQQLLIG--AYAKALEIIPRQLCD 451

  Fly   470 NAGVDPNEVLRRV----LKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATT 530
            |||.|...:|.::    .:|...||.|.......|.....:.:|..|..:|:|:|:..|.|:.:.
Mouse   452 NAGFDATNILNKLRARHAQGGMWYGVDINNENIADNFQAFVWEPAMVRINALTAASEAACLIVSV 516

  Fly   531 EVLI-----TKQPTKP 541
            :..|     |..|..|
Mouse   517 DETIKNPRSTVDPPAP 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	125/577 (22%)
Cct7	NP_031664.3	TCP1_eta	5..525	CDD:239456	128/592 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	523..544		3/10 (30%)