Protein Alignment Hsp60D and Cct6b

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_033969.2
• Gene: Cct6b / 12467
• MGIID: 1329013
• Length: 531
• Species: Mus musculus
• Alignment Length: 591
• Identity: 127/591 - (21%)
• Similarity: 218/591 - (36%)
• Gaps: 158/591 - (26%)

  Fly    23 GAE-ARCLLMQGVNV-----LANAVATTLGPKGRNVLIEQLLISP----RITKDGITVANNVQLG 77
            ||| .|......||:     |.:.:..||||||    ..::|:|.    ::||||..:.:.:|:
Mouse    10 GAEVTRSQAALAVNICAARGLQDVLRPTLGPKG----ALKMLVSGAGDIKLTKDGNVLLHEMQI- 69

  Fly    78 NRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQ-------GMH---------------- 119
               |.....::.:.....::..|||||:..::...:..|       |:|
Mouse    70 ---QHPTASIIAKVAAAQDHVTGDGTTSNVLIIGELLKQADLYISEGLHPRIITEGFDVAKTKAL 131

  Fly   120 -VLRQSKVNVQLLREGILEGSRAVCDALGEMSQSVDTIGQVEAVAKVALNGDERLAELIGDIILE 183
             ||.:.||..::.||.:|:.:|              |..|.:..|::|    :.|.|.:.|.:|.
Mouse   132 EVLDEIKVQKEMKREILLDVAR--------------TSLQTKVHAELA----DILTEAVVDSVLA 178

  Fly   184 LGDSG-------VILLKESHSPFDEAKIQEGITIASGYYSPFFAKQSHTLELENCLLLLTLAKI- 240
            :...|       |.:::..|....:.::..|:.:..|...|...||.....:..|.:.|...|.
Mouse   179 IRRPGVPIDLFMVEIVEMRHKSETDTQLIRGLVLDHGARHPRMRKQVRDAYILTCNVSLEYEKTE 243

  Fly   241 -------------------------DQVEQILPALELARLKERPLLIIAKNFGSD--LLKILVLN 278
                                     |:|::|:...:....:.....::....|.|  .|::|..:
Mouse   244 VSSGFFYKTVEEKEKLVKAERKFIEDRVQKIIDLKQKVCAESNKGFVVINQKGIDPVSLEMLAKH 308

  Fly   279 NLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGE---VMEAVVDAKE 340
            |:     |...:|      :...:|.:..|.||..:   :|...||||.||.   |.|..
Mouse   309 NI-----VALRRA------KRRNLERLTLACGGLAV---NSFEGLSEECLGHAGLVFEYA----- 354

  Fly   341 THLLQPINVNEEQVQCRIQDIRELIDEAFTDVE--LDRLKTRLGRLQGHLATIFVGGTSELEVSE 403
                                   |.:|.||.:|  ::.|.          .|:.|.|.::..:.:
Mouse   355 -----------------------LGEEKFTFIEDCVNPLS----------VTLLVKGPNKHTLIQ 386

  Fly   404 RKDRFNDALHAVRVAISDG-VVPGGGTAYLRCIPVLDELPPTDIMELQVGREIVKDALRLPCYTI 467
            .||...|.|.||:.||.|| ||||.|...:.....|..........:::|.:...|||.:....:
Mouse   387 IKDALRDGLRAVKNAIEDGCVVPGAGAVEVAIAEALVNYKHRVQGRVRLGIQAFADALLIIPKVL 451

  Fly   468 ARNAGVDPNEVLRRV----LKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIA-SLL 527
            |:|:|.|..|.|.::    .:.....|.|...||.......||.|...|.:..:.|...|| ::|
Mouse   452 AQNSGYDLQETLIKIQTKHAESKELLGIDLNTGEPMAAAEAGIWDNYCVKKHLLHSCTVIATNIL 516

  Fly   528 ATTEVL 533
            ...|::
Mouse   517 LVDEIM 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	127/591 (21%)
Cct6b	NP_033969.2	chap_CCT_zeta	3..530	CDD:274088	127/591 (21%)