Protein Alignment Hsp60D and Cct5

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_031663.1
• Gene: Cct5 / 12465
• MGIID: 107185
• Length: 541
• Species: Mus musculus
• Alignment Length: 546
• Identity: 119/546 - (21%)
• Similarity: 221/546 - (40%)
• Gaps: 127/546 - (23%)

  Fly    23 GAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISP----RITKDGITVANNVQLGNRRQDM 83
            |.||....:.....:||.:.|:|||.|    ::::::..    .||.||.|:.:.:.:.::...:
Mouse    30 GLEALKSHIMAAKAVANTMRTSLGPNG----LDKMMVDKDGDVTITNDGATILSMMDVDHQIAKL 90

  Fly    84 GVQLLRQATNNTNNKVGDGTTTATIL-------ARGIACQGMHVLRQSKVNVQLLREGILEGSRA 141
            .|:|    :.:.::::|||||...:|       |..:..:|:|.:|        :.:|..:.:|.
Mouse    91 MVEL----SKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIR--------IADGYEQAARI 143

  Fly   142 VCDALGEMSQSV---------------DTIGQV------EAVAKVALNG------------DERL 173
            ....|.::|..|               .|:|..      ..:|::|:|.            |..|
Mouse   144 AIQHLDKISDKVLVDINNPEPLIQTAKTTLGSKVINSCHRQMAEIAVNAVLTVADMERRDVDFEL 208

  Fly   174 AELIGDIILELGDS----GVILLKE-SHSPFDEAKIQEGITIASGYYSPFFAKQSHTLELENCLL 233
            .::.|.:...|.|:    |||:.|: ||....:..:...|.|.:..:.|...|..|.|::.:...
Mouse   209 IKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVVDAKIAILTCPFEPPKPKTKHKLDVMSVED 273

  Fly   234 LLTLAKI--DQVEQILPALELARLKE--RPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSF 294
            ...|.|.  ::.|::     :.::||  ..|.|....|..:...:|:.|.|..   |..|..|
Mouse   274 YKALQKYEKEKFEEM-----IKQIKETGANLAICQWGFDDEANHLLLQNGLPA---VRWVGGP-- 328

  Fly   295 GDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQ 359
                  |:|.||.||||.::   ...::|:.|.||  ...||        |.|:....:.:..:
Mouse   329 ------EIELIAIATGGRIV---PRFSELTSEKLG--FAGVV--------QEISFGTTKDKMLV- 373

  Fly   360 DIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVAISDG-V 423
                          :::.|      .....|||:.|.:::.:.|.|...:|||..:|..|.|. |
Mouse   374 --------------IEKCK------NSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRV 418

  Fly   424 VPGGGTAYLRC-IPVLDELPPTDIMELQVGREIVKDALRLPCYTIARNAGVDPNEVL-----RRV 482
            |.|||.|.:.| :.|..|......:| |.......|||.:....::.|:|::|.:.:     |:|
Mouse   419 VYGGGAAEISCALAVSQEADKCPTLE-QYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQV 482

  Fly   483 LKGSGNYGYDAAAGEFGDLVVRGIVD 508
            .:.:...|.|.......|:..:.:::
Mouse   483 KESNPALGIDCLHKGSNDMQYQHVIE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	119/546 (22%)
Cct5	NP_031663.1	TCP1_epsilon	10..535	CDD:239455	119/546 (22%)