Protein Alignment Hsp60D and Cct4

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_033967.1
• Gene: Cct4 / 12464
• MGIID: 104689
• Length: 539
• Species: Mus musculus
• Alignment Length: 555
• Identity: 118/555 - (21%)
• Similarity: 225/555 - (40%)
• Gaps: 88/555 - (15%)

  Fly    24 AEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPRITKDGITVANNVQLGNRRQDMGVQLL 88
            |:.|...:.....:|:|:.|:|||||.:.:|:.......||.||.|:...:|:.:....|.|:|
Mouse    31 AQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVEL- 94

  Fly    89 RQATNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVCDALGEMSQSV 153
               :...:.:.|||||:..|:| |........|.|..::..::.|...:......:.|.:||:.|
Mouse    95 ---SKAQDIEAGDGTTSVVIIA-GSLLDSCTKLLQKGIHPTIISESFQKALEKGLEILTDMSRPV 155

  Fly   154 -----DTI---GQVEAVAKVALNGDERLAELIGDIILELGDSG---------VILLKESHSPFDE 201
                 :|:   ......:||.......|:.:..:.::::.|..         :.::|:.....|:
Mouse   156 QLSDRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDD 220

  Fly   202 AKIQEGITIA-----SGYYSPFFAK--------QSHTLELENCLLLLTLAKIDQV--EQILPALE 251
            .::.||:.:.     ||......||        .:...:::|.:::...|::|:|  |:....|.
Mouse   221 CELVEGLVLTQKVANSGITRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILN 285

  Fly   252 LARLKERP---LLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHL 313
            |.:..::.   :|:|.|:...|.|..|.|:.| .::::..||
Mouse   286 LVKQIKKTGCNVLLIQKSILRDALSDLALHFL-NKMKIMVVK----------------------- 326

  Fly   314 LEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLK 378
                    |:..||:..:.:.:......|:        :|....:....||.:|...:......|
Mouse   327 --------DVEREDIEFICKTIGTKPVAHI--------DQFTADMLGSAELAEEVSLNGSGKLFK 375

  Fly   379 TRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVRVAISD-GVVPGGGTAYLRCIPVLDELP 442
            .......|...||.|.|:::|.:.|.:...:|||..:|..:.. .::.|||...:.....|.|..
Mouse   376 ITGCTSPGKTVTIVVRGSNKLVIEEAERSIHDALCVIRCLVKKRALIAGGGAPEIELALRLTEYS 440

  Fly   443 PT-DIMELQVGREIVKDALRLPCYTIARNAGVDP----NEVLRRVLKGSGNYGYDAAAGEFGDLV 502
            .| ..||....|... ||:.:...|:|.|||::|    .|:..|..:|....|.:...|...:::
Mouse   441 RTLSGMESYCVRAFA-DAMEVIPSTLAENAGLNPISTVTELRNRHAQGEKTTGINVRKGGISNIL 504

  Fly   503 VRGIVDPTKVLQSAMTSAA-GIASLLATTEVLITK 536
            ...:|.|..|..||:|.|. .:.|:|...:|:.|:
Mouse   505 EEMVVQPLLVSVSALTLATETVRSILKIDDVVNTR 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	117/553 (21%)
Cct4	NP_033967.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		TCP1_delta	25..538	CDD:239454	117/552 (21%)