Protein Alignment Hsp60D and Cct3

DIOPT Version :10

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_033966.1
• Gene: Cct3 / 12462
• MGIID: 104708
• Length: 545
• Species: Mus musculus
• Alignment Length: 574
• Identity: 117/574 - (20%)
• Similarity: 214/574 - (37%)
• Gaps: 135/574 - (23%)

  Fly    31 MQGVNVLANAVATTLGPKGRNVLIEQLLISPR----ITKDGITVANNVQLGNRRQDMGVQLLRQA 91
            :.....:|:.:.|.||||.    :.::|:.|.    :|.||..:...:|:    |....:.:.:.
Mouse    27 INAAKTIADIIRTCLGPKS----MMKMLLDPMGGIVMTNDGNAILREIQV----QHPAAKSMIEI 83

  Fly    92 TNNTNNKVGDGTTTATILARGIACQGMHVLRQSKVNVQLLREGILEGSRAVCD----ALGEMSQS 152
            :...:.:||||||:..|||..:.....|.|.|     |:....::...|...|    .|.::|..
Mouse    84 SRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQ-----QMHPTVVISAYRMALDDMISTLKKISTP 143

  Fly   153 VDTIGQ---------------------------VEAVAKVAL--NGDE--------RLAELIGDI 180
            ||...:                           ::||..|..  ||.:        |:.::.|.|
Mouse   144 VDVNNREMMLSIINSSITTKVISRWSSLACNIALDAVKTVQFEENGRKEIDIKKYARVEKIPGGI 208

  Fly   181 ILELGDS----GVILLKESHSPFDEAKIQEGITIASGYYSPFFAKQSHT-LEL---ENCLLLLTL 237
            |   .||    ||::.|:...|.....|:....:.......:...:|.| :|:   |:...:|.:
Mouse   209 I---EDSCVLRGVMINKDVTHPRMRRYIKNPRIVLLDSSLEYKKGESQTDIEITREEDFTRILQM 270

  Fly   238 AKIDQVEQILPALELARLKERPLLIIAKNFGSDLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEM 302
            .: :.:.|:..  ::.:||  |.::|.:...|||.:..::     |..|.|::.....|.
Mouse   271 EE-EYIHQLCE--DIIQLK--PDVVITEKGISDLAQHYLM-----RANVTAIRRVRKTDN----- 320

  Fly   303 EDIAFATGGHLLEDASSLADLSEEDLGEVMEAVVDAKETHLLQPINVNEEQVQCRIQDIRELIDE 367
            ..||.|.|..::   |...:|.|:|:|                        ....:.:|:::.||
Mouse   321 NRIARACGARIV---SRPEELREDDVG------------------------TGAGLLEIKKIGDE 358

  Fly   368 AFTDVELDRLKTRLGRLQGHLATIFVGGTSELEVSERKDRFNDALHAVR-VAISDGVVPGGGTAY 431
            .||.:...:        .....||.:.|.|:..:||.:....||:...| |.:...:|||||.:.
Mouse   359 YFTFITDCK--------DPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLVPGGGASE 415

  Fly   432 LRCIPVLDELPPTDIMELQVGRE-----IVKDALRLPCYTIARNAGVDPNEVL-----RRVLKGS 486
            :.....|     |:..:...|.|     .|..||.:...|:.:|.|.....:|     :...:..
Mouse   416 MAVAHAL-----TEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRAKHTQESC 475

  Fly   487 GNYGYDAAAGEFGDLVVRGIVDPTKVLQSAMTSAAGIASLLATTEVLITKQPTK 540
            ..:|.:...|...|:...||.:|..|......:|...|.||...:.:::....|
Mouse   476 ETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKKK 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	GroEL	18..536	CDD:239460	116/568 (20%)
Cct3	NP_033966.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..24
		chap_CCT_gamma	6..529	CDD:274085	116/572 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	526..545		1/4 (25%)