Protein Alignment Hsp60D and CCT7

DIOPT Version :9

• Sequence 1: NP_609656.1
• Gene: Hsp60D / 34763
• FlyBaseID: FBgn0032525
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_006420.1
• Gene: CCT7 / 10574
• HGNCID: 1622
• Length: 543
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 127/609 - (20%)
• Similarity: 231/609 - (37%)
• Gaps: 163/609 - (26%)

  Fly     1 MLSRLGRSGRAGVRTFANDIRFGAEARCLLMQGVNVLANAVATTLGPKGRNVLIEQLLISPR--- 62
            :|.:.|.....|:....::|     :.|      .|:|.||.|||||:|    :::|::..|
Human     7 ILLKEGTDSSQGIPQLVSNI-----SAC------QVIAEAVRTTLGPRG----MDKLIVDGRGKA 56

  Fly    63 -ITKDGITVANNVQLGNRRQDMGVQLLRQATNNTNNKVGDGTTTATILARGIACQ-------GMH 119
             |:.||.|:...:.:.:    ...:.|.....:.:.:||||||:.|:||.....|       |:|
Human    57 TISNDGATILKLLDVVH----PAAKTLVDIAKSQDAEVGDGTTSVTLLAAEFLKQVKPYVEEGLH 117

  Fly   120 ---VLRQSKVNVQLLREGILEGSRAVCDALGEMSQSVDTIGQVEAVAKVALNG-DERL------- 173
               ::|..:...||....|.|.:..|        :..|.:.|.:.:.|.|:.. ..:|
Human   118 PQIIIRAFRTATQLAVNKIKEIAVTV--------KKADKVEQRKLLEKCAMTALSSKLISQQKAF 174

  Fly   174 -AELIGDIILELGD----SGVILLKESHSPFDEAKIQEGITI------------ASGYYSPFFAK 221
             |:::.|.::.|.|    ..:.:.|......:::::..|:..            ...|::|..|.
Human   175 FAKMVVDAVMMLDDLLQLKMIGIKKVQGGALEDSQLVAGVAFKKTFSYAGFEMQPKKYHNPKIAL 239

  Fly   222 QSHTLEL----ENCLLLLTLAK-------------IDQVEQILPALELARLKERPLLIIAKNFGS 269
            .:..|||    :|..:.:...:             .|::|:|..:.....|.:.|:..:|..:.:
Human   240 LNVELELKAEKDNAEIRVHTVEDYQAIVDAEWNILYDKLEKIHHSGAKVVLSKLPIGDVATQYFA 304

  Fly   270 DLLKILVLNNLQGRVQVCAVKAPSFGDEQCEEMEDIAFATGGHLLEDASSLADLSEEDLGEVMEA 334
            |            |...||.:.|.      |:::....|.||.:   .:|:..||.:.||
Human   305 D------------RDMFCAGRVPE------EDLKRTMMACGGSI---QTSVNALSADVLG----- 343

  Fly   335 VVDAKETHLLQPINVNEEQVQCRIQDIRELIDEAFTDVELDRLKTRLGRLQGHLATIFVGGTSEL 399
                                :|::      .:|  |.:..:|.....|..:....|..:.|.:|.
Human   344 --------------------RCQV------FEE--TQIGGERYNFFTGCPKAKTCTFILRGGAEQ 380

  Fly   400 EVSERKDRFNDALHAVRVAI-SDGVVPGGGTA----------YLRCIPVLDELPPTDIMELQVGR 453
            .:.|.:...:||:..||.|| :|.||.|||..          |.|.||        ...:|.:|
Human   381 FMEETERSLHDAIMIVRRAIKNDSVVAGGGAIEMELSKYLRDYSRTIP--------GKQQLLIG- 436

  Fly   454 EIVKDALRLPCYTIARNAGVDPNEVLRRV----LKGSGNYGYDAAAGEFGDLVVRGIVDPTKVLQ 514
             ....||.:....:..|||.|...:|.::    .:|...||.|....:..|.....:.:|..|..
Human   437 -AYAKALEIIPRQLCDNAGFDATNILNKLRARHAQGGTWYGVDINNEDIADNFEAFVWEPAMVRI 500

  Fly   515 SAMTSAAGIASLLATTEVLITKQP 538
            :|:|:|:..|.|:.:.:..| |.|
Human   501 NALTAASEAACLIVSVDETI-KNP 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsp60D	NP_609656.1	PTZ00114	13..546	CDD:185455	124/597 (21%)
		GroEL	18..536	CDD:239460	122/588 (21%)
CCT7	NP_006420.1	TCP1_eta	5..525	CDD:239456	127/609 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..543		127/609 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810