DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and PHS1

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_012438.1	Gene:	PHS1 / 853348	SGDID:	S000003633	Length:	217	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	51/209 - (24%)
Similarity:	93/209 - (44%)	Gaps:	20/209 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 YMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTKGS 215
            ::..|||...||:.|::.::..||.:.|..:.   :....|....:|....:|:::...|..:..
Yeast    11 FLPLYNLLSAVGWSYLLYLVISLYPKVGQPAF---FYQTKNVATLVQCGAIIEIINSFLGVVRSP 72

  Fly   216 PVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFII--WSLVELVRYPYYLAQLLGREVG--LL 276
            .:....|||.|..::..:..:.|.......|.|:.::  ||:.|:|||.||...|:.:...  :|
Yeast    73 LLTTVAQVSSRLLVVLGIFQLLPNTSGVQSVVYISLLLAWSITEIVRYLYYFFMLVFKNGAPKIL 137

  Fly   277 TWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLFLKIYLMLLIIPG 341
            ..|||.::..|||.|:..|..|:...:...|          :.:::.:..:|   |..||..|||
Yeast   138 ILLRYNLFWILYPTGVASELRIIYCALNAAE----------SQYSLLYKRIL---IAAMLAYIPG 189

  Fly   342 SYLVMSHMAKLRSK 355
            ..::..||...|.|
Yeast   190 FPMLFLHMVAQRKK 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	41/163 (25%)
PHS1	NP_012438.1	Ptpl	1..217	CDD:227525	51/209 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344691
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700