DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and hacd4

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_001186940.2	Gene:	hacd4 / 561303	ZFINID:	ZDB-GENE-030131-3627	Length:	222	Species:	Danio rerio

Alignment Length:	224	Identity:	69/224 - (30%)
Similarity:	109/224 - (48%)	Gaps:	20/224 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   140 LGYIKEKTKKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEV 204
            ||:|       |:..|||..|.|:.:|...|...:...|.|:...|:..|.......|||..||:
Zfish     5 LGFI-------YLFSYNLLQFCGHTWIFANMTARFLSFGKDAQFGTFYFVAVMMGACQLLSLLEL 62

  Fly   205 MHPMFGYTKGSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLL 269
            .|...|:.:......|.||..||.:|||:|.:| ...:||:|...|.:|:::.|:|||:.|..|:
Zfish    63 FHIADGFDECRLFPRFMQVIERNVLLFLLISLE-EFQSKPIVCVQFYLWNILGLLRYPHRLFCLI 126

  Fly   270 GREVGLLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEE---TKRFTVEMPNPWNITFDMVLFLK 331
            |.....:.|:..|:.||:|.|..:.|||.:...:||:.|   |.....::|.|      |.::..
Zfish   127 GTPYFKMLWVHQTLTIPVYLMSAVTEGISIFLMLPYLSESEGTDSVQPKVPAP------MYMYSP 185

  Fly   332 IYLM---LLIIPGSYLVMSHMAKLRSKKL 357
            ..:|   ||::.||.|.:..:.|.|.:.|
Zfish   186 YIVMSWILLLVLGSSLTVLLLLKERKENL 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	53/165 (32%)
hacd4	NP_001186940.2	PTPLA	55..216	CDD:321828	54/167 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11035
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950