DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hacd2 and Hacd4

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	XP_006238438.1	Gene:	Hacd4 / 362540	RGDID:	1310339	Length:	237	Species:	Rattus norvegicus

Alignment Length:	220	Identity:	67/220 - (30%)
Similarity:	112/220 - (50%)	Gaps:	14/220 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   148 KKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYT 212
            |..|:..|.|..|.|:.:|:..|.|.::..|.||:..|:..:|...:..|.:..||::|...|..
  Rat    16 KSAYLFIYYLIQFCGHSWILTNMTVRFFSFGKDSMVDTFYAIGLVMRVCQSISLLELLHIYIGIE 80

  Fly   213 KGSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREVGLLT 277
            .......|.|::.|..|||.:|..:..:..|.||..:||.|:|:::|||.|.:..::|....:||
  Rat    81 SNQLFPKFLQLTERIIILFGVITSQEEVQEKYVVCVLFIFWNLLDMVRYTYSMLSVIGTSYAVLT 145

  Fly   278 WLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLF----LKIYLMLLI 338
            ||..|:|:|:||:.:|.|...:.:::||.|...:.:..:|      ||:..:    ||:|||:|.
  Rat   146 WLSQTLWMPIYPLCVLAEAFTIYQSLPYFELFGKNSTMLP------FDISTYFPYVLKLYLMMLF 204

  Fly   339 IPGSYLVMSHMAKLRSKKLGKGRAK 363
            |    .:.....|..|:.|...|.|
  Rat   205 I----AIFIRKEKTSSEDLLSNRRK 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	50/163 (31%)
Hacd4	XP_006238438.1	PTPLA	65..209	CDD:282269	48/153 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345262
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11035
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.810