DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and hacd2

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_956155.1	Gene:	hacd2 / 334121	ZFINID:	ZDB-GENE-030131-6053	Length:	239	Species:	Danio rerio

Alignment Length:	224	Identity:	69/224 - (30%)
Similarity:	114/224 - (50%)	Gaps:	7/224 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 ELGYIKEK----TKKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLL 199
            |.|:.|:|    ....|::.||:.|..|:|.|.|.:...|...|  |....|.::....||.|..
Zfish    10 ESGHKKKKGPGTLATAYLVIYNVIMTAGWLVIAVGLVRAYLARG--SYHGLYYSIEKPLKFFQTG 72

  Fly   200 QYLEVMHPMFGYTKGSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYY 264
            ..||::|...|....|.|:..|||..|.|:.:.:......:.::..|....:.|::.|::||.:|
Zfish    73 ALLEILHCAVGIVPSSVVLTGFQVMSRVFLTWAVTHSVREVQSEDSVLLFVVAWTVTEIIRYSFY 137

  Fly   265 LAQLLGREVGLLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLF 329
            ...||.....|:.|.|||.:|.|||||::.|.:.:...:||:::...:::.:||.:|.:||...|
Zfish   138 TFSLLNHLPYLIKWARYTFFIVLYPMGVMGELLTIYAALPYVQKAGLYSITLPNKYNFSFDYHTF 202

  Fly   330 LKIYLMLLIIPGSYLVMSHMAKLRSKKLG 358
            | |::|:..||....:..||.:.|.|.||
Zfish   203 L-IFVMISYIPLFPQLYFHMMRQRKKVLG 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	49/159 (31%)
hacd2	NP_956155.1	PTPLA	70..229	CDD:282269	49/159 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820