DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and Hacd1

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	NP_038963.3	Gene:	Hacd1 / 30963	MGIID:	1353592	Length:	248	Species:	Mus musculus

Alignment Length:	235	Identity:	73/235 - (31%)
Similarity:	121/235 - (51%)	Gaps:	20/235 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 EKEYADLQKRELGYIKEKTKKVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAF 193
            |||.|. ::|.||.:    ...::.|||:||..|:|.:.:.|...|...|...  ..|.::....
Mouse    18 EKEAAG-KRRRLGLL----ATAWLTFYNIAMTAGWLVLAIAMVRFYMEKGTHR--GLYKSIQKTL 75

  Fly   194 KFIQLLQYLEVMHPMFGYTKGSPVVPFFQVSGRNFILFLMI-DMEPRMYAKPVVFYVFIIWSLVE 257
            ||.|....|||:|.:.|....|.:|...|||.|.|:::|:. .::|....:.||.:: :.|::.|
Mouse    76 KFFQTFALLEVVHCLIGIVPTSVLVTGVQVSSRIFMVWLITHSIKPIQNEESVVLFL-VSWTVTE 139

  Fly   258 LVRYPYYLAQLLGREVGLLTWLRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNI 322
            :.||.:|...||......:.|.||.::|.|||:|:..|.:.:...:||::::..|:|.:||.:|:
Mouse   140 ITRYSFYTFSLLDHLPHFIKWARYNLFIILYPVGVAGELLTIYAALPYVKKSGMFSVRLPNKYNV 204

  Fly   323 TFDMVLFLKIYLMLLIIPGSYL-----VMSHMAKLRSKKL 357
            :||      .|..|||...||:     :..||.:.|.|.|
Mouse   205 SFD------YYYFLLITMASYIPLFPQLYFHMLRQRRKVL 238

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	52/165 (32%)
Hacd1	NP_038963.3	PTPLA	79..238	CDD:282269	52/165 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5198
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810