DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hacd2 and hacd4

DIOPT Version :9

Sequence 1:	NP_609655.2	Gene:	Hacd2 / 34762	FlyBaseID:	FBgn0032524	Length:	371	Species:	Drosophila melanogaster
Sequence 2:	XP_017953281.1	Gene:	hacd4 / 100490902	XenbaseID:	XB-GENE-995575	Length:	224	Species:	Xenopus tropicalis

Alignment Length:	217	Identity:	65/217 - (29%)
Similarity:	114/217 - (52%)	Gaps:	10/217 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 KVYMIFYNLAMFVGYLYIMVVMGVLYYRDGVDSIGKTYANVGNAFKFIQLLQYLEVMHPMFGYTK 213
            |.|:..|.|..|.|:.:|...|...:...|.|:...|:.::|...:..|||..||:.|.:.|..:
Frog     8 KTYLSIYYLLQFCGHSWIFTNMTARFLFFGQDAFADTFYSIGLVMQGCQLLSVLELAHILLGVEQ 72

  Fly   214 GSPVVPFFQVSGRNFILFLMIDMEPRMYAKPVVFYVFIIWSLVELVRYPYYLAQLLGREVGLLTW 278
            .|.:..||||:.|..|||::|..:..:.:|.:|..:|.:|:|.:::||||.:...:|.:...||.
Frog    73 YSLLPTFFQVTERLIILFVVITSQEEVQSKYIVCALFFLWNLWDVIRYPYDMLAAVGIDYSALTR 137

  Fly   279 LRYTIWIPLYPMGILCEGIIVLRNIPYIEETKRFTVEMPNPWNITFDMVLFLKIYLMLLIIPGSY 343
            |::|.||..||:.:|.|...|..::||.|....::.:|.:|.:::|.....|.:||:..:: |.:
Frog   138 LKHTWWILAYPLSVLAEAYTVYESLPYFESRGTYSFKMESPVSLSFHFPYILTLYLIFQLV-GMF 201

  Fly   344 LVMS---------HMAKLRSKK 356
            .:.|         ...||:.||
Frog   202 YICSCQWWERKQYFRRKLKLKK 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hacd2	NP_609655.2	p23_hB-ind1_like	6..114	CDD:107222
Hacd2	NP_609655.2	PTPLA	197..357	CDD:282269	53/169 (31%)
hacd4	XP_017953281.1	PTPLA	56..217	CDD:398198	49/161 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1458293at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010