DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tehao and AT5G05400

DIOPT Version :9

Sequence 1:	NP_001285901.1	Gene:	Tehao / 34761	FlyBaseID:	FBgn0026760	Length:	795	Species:	Drosophila melanogaster
Sequence 2:	NP_196159.1	Gene:	AT5G05400 / 830422	AraportID:	AT5G05400	Length:	874	Species:	Arabidopsis thaliana

Alignment Length:	883	Identity:	164/883 - (18%)
Similarity:	297/883 - (33%)	Gaps:	328/883 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   107 DLLKTLGVQTVKTIIFRDRT---LETVVTR-----DVLNSGNGYMETSQPENITTWHFGSVPGLK 163
            ||||.:.||..:.:...|..   |..|.:|     |:|:..:     .:.:|:....:.|    |
plant    52 DLLKRIKVQEDRGLNLLDEVQQWLSEVESRVCEAHDILSQSD-----EEIDNLCCGQYCS----K 107

  Fly   164 KFKF-----------------------FSHV------PELQESIFH----GFDTLRD------LH 189
            :.|:                       |..|      |:::|.:||    |.:.:.:      :.
plant   108 RCKYSYDYSKSVINKLQDVENLLSKGVFDEVAQKGPIPKVEERLFHQEIVGQEAIVESTWNSMME 172

  Fly   190 LSVNVTTLPG-------NMLSTVNGTLKTLTIE---SPGIVSFGNPLLRELQQLRNLSLALIHPF 244
            :.|.:..:.|       .:||.:|...:|::.:   :..:|...||.::.:|:
plant   173 VGVGLLGIYGMGGVGKTTLLSQINNKFRTVSNDFDIAIWVVVSKNPTVKRIQE------------ 225

  Fly   245 HERDKQLQPHFFGSMTNLEEVRLASATSSVNRSMFKGTNKLQLI-------------------KM 290
             :..|:|..:..|.....|.    ...|::.||:   .||..::                   |.
plant   226 -DIGKRLDLYNEGWEQKTEN----EIASTIKRSL---ENKKYMLLLDDMWTKVDLANIGIPVPKR 282

  Fly   291 NGNDDLM-----ELPGEIFLDQVNLKTLDLSCNAIVTLHEDVFKGLGNLTLLDL-SKNRLTNLSS 349
            ||:....     |:.|::.:|    |.::::|    .:.:|.:         || ::|....|.|
plant   283 NGSKIAFTSRSNEVCGKMGVD----KEIEVTC----LMWDDAW---------DLFTRNMKETLES 330

  Fly   350 TIFAPLTSLNVLR--------LN--------KNSL------TAMSPSVFQDVVSLNYIEMVNTQF 392
            ....|..:.::.|        ||        |.|:      ..:...:..|::|:
plant   331 HPKIPEVAKSIARKCNGLPLALNVIGETMARKKSIEEWHDAVGVFSGIEADILSI---------- 385

  Fly   393 YGATLLMNYEAVVCTNDEACQYKSA------EWQCDPRCICWVQRSV--GSLIVDCRGTSLEELP 449
                |..:|:.:.|...::|...||      |...|.....||.:.:  ||..::.:|.::  :.
plant   386 ----LKFSYDDLKCEKTKSCFLFSALFPEDYEIGKDDLIEYWVGQGIILGSKGINYKGYTI--IG 444

  Fly   450 DLPRTTLL-------------------------------STVLKV-GNNSLTSLPTVSEHSGYAN 482
            .|.|..||                               ..||.| .|..|..:|.:.:......
plant   445 TLTRAYLLKESETKEKVKMHDVVREMALWISSGCGDQKQKNVLVVEANAQLRDIPKIEDQKAVRR 509

  Fly   483 VSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGC 547
            :|.::   |.:.........| .|..|.:|.|:::.:|.|||..:.   ..|.|.||.||.....
plant   510 MSLIY---NQIEEACESLHCP-KLETLLLRDNRLRKISREFLSHVP---ILMVLDLSLNPNLIEL 567

  Fly   548 ESLSLLFFVR----------TNPQRVRDIADIVCTKQKKSFQQMEAFEL--CPSYVLLISCVVGG 600
            .|.|.|:.:|          :.|..:..:.:::....:.::.....:|:  .|:..:| .....|
plant   568 PSFSPLYSLRFLNLSCTGITSLPDGLYALRNLLYLNLEHTYMLKRIYEIHDLPNLEVL-KLYASG 631

  Fly   601 LVIV------------ICLLTVFYLMFQQELKIWL-------YNNNLCLWWVSEEELDKDKTYD- 645
            :.|.            :.|||: .|.....|:|:|       |...|        .||:...|.
plant   632 IDITDKLVRQIQAMKHLYLLTI-TLRNSSGLEIFLGDTRFSSYTEGL--------TLDEQSYYQS 687

  Fly   646 -----AFISYSHKDEELISKLLPKLE-----------SGP-----------HPFRL--C--LHDR 679
                 |.|| |.:..|:....:||:|           .||           ...||  |  |.|.
plant   688 LKVPLATIS-SSRFLEIQDSHIPKIEIEGSSSNESEIVGPRVRRDISFINLRKVRLDNCTGLKDL 751

  Fly   680 DWLVGD---------CIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRII 735
            .|||..         |:|:                    |:.:.:|.|     ::.||...:...
plant   752 TWLVFAPHLATLYVVCLPD--------------------IEHIISRSE-----ESRLQKTCELAG 791

  Fly   736 IILYRELEHMNGIDSELRAYLKLNTYLKWGDPLFWSKL 773
            :|.:||||.:.     ||...:|.:..:  |||.:.||
plant   792 VIPFRELEFLT-----LRNLGQLKSIYR--DPLLFGKL 822

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_001285901.1	leucine-rich repeat	185..207	CDD:275380	4/34 (12%)
		leucine-rich repeat	209..232	CDD:275380	4/25 (16%)
		leucine-rich repeat	233..261	CDD:275380	3/27 (11%)
		LRR_RI	<261..370	CDD:238064	26/155 (17%)
		leucine-rich repeat	262..284	CDD:275380	4/21 (19%)
		leucine-rich repeat	285..309	CDD:275380	6/47 (13%)
		LRR_8	309..368	CDD:290566	13/75 (17%)
		leucine-rich repeat	310..333	CDD:275380	3/22 (14%)
		leucine-rich repeat	334..357	CDD:275380	6/23 (26%)
		leucine-rich repeat	358..381	CDD:275380	6/44 (14%)
		leucine-rich repeat	445..482	CDD:275380	10/68 (15%)
		LRR_8	459..516	CDD:290566	13/57 (23%)
		leucine-rich repeat	483..505	CDD:275380	3/21 (14%)
		LRR_4	486..521	CDD:289563	6/34 (18%)
		TIR	643..779	CDD:214587	39/172 (23%)
AT5G05400	NP_196159.1	NB-ARC	159..429	CDD:279299	51/320 (16%)
		leucine-rich repeat	507..528	CDD:275378	3/24 (13%)
		LRR_8	527..582	CDD:290566	19/58 (33%)
		leucine-rich repeat	529..552	CDD:275378	8/25 (32%)
		leucine-rich repeat	553..575	CDD:275378	9/21 (43%)
		LRR_8	575..627	CDD:290566	5/52 (10%)
		leucine-rich repeat	576..598	CDD:275378	2/21 (10%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D282372at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010