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Protein Alignment Tehao and TLR5

DIOPT Version :9

Sequence 1:	NP_001285901.1	Gene:	Tehao / 34761	FlyBaseID:	FBgn0026760	Length:	795	Species:	Drosophila melanogaster
Sequence 2:	NP_003259.2	Gene:	TLR5 / 7100	HGNCID:	11851	Length:	858	Species:	Homo sapiens

Alignment Length:	728	Identity:	174/728 - (23%)
Similarity:	293/728 - (40%)	Gaps:	168/728 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 FRDRTLETVVTRDVLNSGNGYMETSQPENITTWHFGSVPGLKKFKFFSHVPELQESIF---HGFD 183
            ||:..||.:   ||  ||||:...      .|.:|.:  .:.|.:.||.:  |...|.   .||.
Human   223 FRNMVLEIL---DV--SGNGWTVD------ITGNFSN--AISKSQAFSLI--LAHHIMGAGFGFH 272

  Fly   184 TLRDLHLSVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERD 248
            .::|    .:..|..|...|:|    :.|.:....:.|..:.:...|:.|:.|:||    :::.:
Human   273 NIKD----PDQNTFAGLARSSV----RHLDLSHGFVFSLNSRVFETLKDLKVLNLA----YNKIN 325

  Fly   249 KQLQPHFFGSMTNLEEVRLA-SATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKT 312
            |.....|:| :.||:.:.|: :....:..|.|.|..|:..|.:..| .:..:..:.|.....|:|
Human   326 KIADEAFYG-LDNLQVLNLSYNLLGELYSSNFYGLPKVAYIDLQKN-HIAIIQDQTFKFLEKLQT 388

  Fly   313 LDLSCNAIVTLH-----EDVFKGLG--------NLT--LLDLSKNRLTNLSSTIF-APLTSLNVL 361
            |||..||:.|:|     .|:|....        |||  |:.||:|||.||....| ..:..|.:|
Human   389 LDLRDNALTTIHFIPSIPDIFLSGNKLVTLPKINLTANLIHLSENRLENLDILYFLLRVPHLQIL 453

  Fly   362 RLNKNSLTAMS--------PSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAE 418
            .||:|..::.|        ||:.|..:..|.:::.
Human   454 ILNQNRFSSCSGDQTPSENPSLEQLFLGENMLQLA------------------------------ 488

  Fly   419 WQCDPRCICWVQRSVGSLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLPT-VSEHSGYAN 482
            |:.:   :||              ...|.|..|       .||.:.:|.|.|||. |..|  ...
Human   489 WETE---LCW--------------DVFEGLSHL-------QVLYLNHNYLNSLPPGVFSH--LTA 527

  Fly   483 VSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPNNTMTLSLSGNPITCGC 547
            :.||.|:.|.||.|...| ||.||..||:..||:.:.:.:..:.|.      .|.::.|...|.|
Human   528 LRGLSLNSNRLTVLSHND-LPANLEILDISRNQLLAPNPDVFVSLS------VLDITHNKFICEC 585

  Fly   548 E-SLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFEL----CPSYVLLISCVVGGLVIVICL 607
            | |..:.:...||.......|||.|. ...||..:..|.|    |....:|.|......::....
Human   586 ELSTFINWLNHTNVTIAGPPADIYCV-YPDSFSGVSLFSLSTEGCDEEEVLKSLKFSLFIVCTVT 649

  Fly   608 LTVFYLMFQQELKIWLYNNNLCL--WWVSEEELDKDK---------TYDAFISYSHKD----EEL 657
            ||:|.:......|.    ...|.  :..::..:.||.         .|||::.:|.||    :..
Human   650 LTLFLMTILTVTKF----RGFCFICYKTAQRLVFKDHPQGTEPDMYKYDAYLCFSSKDFTWVQNA 710

  Fly   658 ISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIA 722
            :.|.|....|..:.|.||..:||::.|:.....|...:.:|::::.::|:||:...|....|..|
Human   711 LLKHLDTQYSDQNRFNLCFEERDFVPGENRIANIQDAIWNSRKIVCLVSRHFLRDGWCLEAFSYA 775

  Fly   723 YQATLQDKRKRIIIIL------YRELEHMNGIDSELRAYLKLNTYLKWGDPL-----FWSKLYYA 776
            ....|.|....:|:::      |:.::|.:     :|.:::...||:|.:.|     |..||
Human   776 QGRCLSDLNSALIMVVVGSLSQYQLMKHQS-----IRGFVQKQQYLRWPEDLQDVGWFLHKL--- 832

  Fly   777 MPHNRRVLKGQKK 789
               ::::||.:|:
Human   833 ---SQQILKKEKE 842

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.