Protein Alignment Tehao and tlr5a

DIOPT Version :10

• Sequence 1: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: XP_001919052.2
• Gene: tlr5a / 403138
• ZFINID: ZDB-GENE-040219-14
• Length: 881
• Species: Danio rerio
• Alignment Length: 657
• Identity: 162/657 - (24%)
• Similarity: 276/657 - (42%)
• Gaps: 161/657 - (24%)

  Fly   203 STVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRL 267
            ||.:|      ::|.||.||         .|.|.|:.          .|....|..:::||::.|
Zfish   283 STFSG------LKSSGIKSF---------DLSNSSIF----------SLTYSVFSYLSDLEQITL 322

  Fly   268 A-SATSSVNRSMFKG-TNKLQLIKMNGNDDLMELPGEI----FLDQVNLKTLDLSCNAIVTLHED 326
            | |..:.:..:.|.| ||   |:|:|.:.:.:   |.|    |.:...|:.||||.|.|..|...
Zfish   323 AESQINKIENNAFLGMTN---LLKLNLSKNFL---GYIDFRTFQNLKGLEVLDLSYNHIWRLGSQ 381

  Fly   327 VFKGLGNLTLLDLSKNRLTNLSSTIFAPLTSLNVLRLNKNSLTAM--SPSV----------FQDV 379
            .|:||.||..|:|:.|.|.::.:  ||.|..|..|.|..|::..:  .|::          |..:
Zfish   382 SFQGLPNLLSLNLTGNSLGHVYT--FATLPKLEKLYLGDNNIQYVYEIPNIAKHLKTLDLQFNQI 444

  Fly   380 VSLN--------YIEMVNTQFYGATLLM----NYEAVVCTNDEACQYKSAEWQCDPRCICWVQRS 432
            .|::        :.::....|.|..||.    |:| |:..|.:......|..|     :.|.:
Zfish   445 ASMSELYTILDEFPQIEEVVFRGNQLLYCPQDNHE-VLSQNIQVLDLSFAGLQ-----VIWSE-- 501

  Fly   433 VGSLIVDCRGTSLEELPDLPRTTLLSTVLKVGNNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLG 497
                     |..|....||.:.    .||.:.:|.|.|||    ...:.:::.|.:.|.:..||.
Zfish   502 ---------GKCLNVFDDLHQL----EVLHLSSNLLQSLP----KDIFKDLTSLLILDLSFNSLK 549

  Fly   498 --SGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPN--NTMT-LSLSGNPITCGCESLSLLFFV- 556
              ..|..|..|..|.:..|.|.|:         :||  :|:: |||..|...|.|:......::
Zfish   550 YLPTDVFPKTLQVLHLDYNSIYSV---------DPNLFSTLSYLSLMNNDFRCDCDLKDFQTWLN 605

  Fly   557 RTNPQRVRDIADIVCTKQKKSF-----------------QQMEAFELCPSYVLLISCVVGGLVIV 604
            :||...|..|.|:.|...:..:                 ::.|...|    ||.|||.|  |:|:
Zfish   606 QTNITFVHSIEDVTCASPEDQYMVPVVSSSIQCEDEEEERRTEKLRL----VLFISCTV--LIIL 664

  Fly   605 ICLLTVFYL-----MFQQELK-IWLYNNNLCLWWVSEEELDKDK-TYDAFISYSHKDEELISK-L 661
            ....|:.|:     :|:...| |..::|.      .:||.|.:. .||.::.:|.:|.:.:.: |
Zfish   665 FSASTIVYISRRGVIFKIYKKLIGKFDNK------PQEEPDANGFLYDVYLCFSSRDMKWVERAL 723

  Fly   662 LPKLES--GPH-PFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAY 723
            |.:|:|  ..| ..|.|..:||::.|:.....:...:..|::.|.|:|:||:...|....|.:|
Zfish   724 LKRLDSQFSEHNTLRCCFEERDFIPGEDHLTNMRNAIQHSRKTICVVSKHFLKDGWCLETFTLA- 787

  Fly   724 QATLQDKRKRIIIIL-------YRELEHMNGIDSELRAYLKLNTYLKWGD-----PLFWSKLYYA 776
            |..:..:.|.|:::|       ||.|::     .:||::::..:||.|.|     ..|:.:|.:.
Zfish   788 QCRMLVELKDILVVLVVGNIPQYRLLKY-----EQLRSFIENRSYLVWPDDGQDLEWFYDQLLHK 847

  Fly   777 MPHNRRV 783
            :..|.:|
Zfish   848 IIRNTKV 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_477438.1	LRR	184..>541	CDD:443914	94/372 (25%)
		leucine-rich repeat	185..207	CDD:275380	2/3 (67%)
		leucine-rich repeat	209..232	CDD:275380	5/22 (23%)
		leucine-rich repeat	233..261	CDD:275380	5/27 (19%)
		leucine-rich repeat	262..284	CDD:275380	8/23 (35%)
		leucine-rich repeat	285..309	CDD:275380	6/27 (22%)
		leucine-rich repeat	310..333	CDD:275380	11/22 (50%)
		leucine-rich repeat	334..357	CDD:275380	8/22 (36%)
		leucine-rich repeat	358..381	CDD:275380	6/34 (18%)
		leucine-rich repeat	445..482	CDD:275380	10/36 (28%)
		leucine-rich repeat	483..505	CDD:275380	6/23 (26%)
		TIR	643..779	CDD:214587	38/151 (25%)
tlr5a	XP_001919052.2	PPP1R42	<47..183	CDD:455733
		leucine-rich repeat	50..72	CDD:275380
		leucine-rich repeat	73..97	CDD:275380
		leucine-rich repeat	98..121	CDD:275380
		leucine-rich repeat	122..147	CDD:275380
		leucine-rich repeat	148..172	CDD:275380
		leucine-rich repeat	173..230	CDD:275380
		LRR	276..>570	CDD:443914	86/344 (25%)
		leucine-rich repeat	297..316	CDD:275380	5/28 (18%)
		leucine-rich repeat	317..340	CDD:275380	7/22 (32%)
		leucine-rich repeat	341..364	CDD:275380	6/25 (24%)
		leucine-rich repeat	365..388	CDD:275380	11/22 (50%)
		leucine-rich repeat	389..410	CDD:275380	8/22 (36%)
		leucine-rich repeat	411..433	CDD:275380	5/21 (24%)
		leucine-rich repeat	434..513	CDD:275380	17/95 (18%)
		leucine-rich repeat	485..499	CDD:275378	2/18 (11%)
		leucine-rich repeat	514..537	CDD:275380	7/30 (23%)
		leucine-rich repeat	538..559	CDD:275380	6/20 (30%)
		leucine-rich repeat	560..581	CDD:275380	7/29 (24%)
		LRRCT	589..638	CDD:214507	9/48 (19%)
		TIR	705..839	CDD:214587	36/139 (26%)