DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tehao and Tlr9

DIOPT Version :9

Sequence 1:NP_001285901.1 Gene:Tehao / 34761 FlyBaseID:FBgn0026760 Length:795 Species:Drosophila melanogaster
Sequence 2:NP_937764.1 Gene:Tlr9 / 338457 RGDID:631352 Length:1032 Species:Rattus norvegicus


Alignment Length:1010 Identity:226/1010 - (22%)
Similarity:348/1010 - (34%) Gaps:339/1010 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 GLSPQCTCAAEGNVVRFHC-----PDEYAMLLEVSEPGASLYMSYYASTELQWLPRFNISSLVKI 92
            ||||          :.|.|     |..:..:..:.|    |.:||...|.:..||    |||..:
  Rat   102 GLSP----------LHFSCRMTIEPKTFLAMRMLEE----LNLSYNGITTVPRLP----SSLTNL 148

  Fly    93 EFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNSGNGYMETSQPENITTWHFG 157
            .    :......:.|.....|:.::: ::|.|              ||.|.:  .|.|      |
  Rat   149 S----LSHTNILVLDASSLAGLHSLR-VLFMD--------------GNCYYK--NPCN------G 186

  Fly   158 SVPGLKKFKFFSHVPELQESIFHGFDTLRDLHLSV---NVTTLPGNMLSTVNGTLKTLTIESPGI 219
            :|             .:....|.|...|  .|||:   |:|.:|..:..::...|.:..:    |
  Rat   187 AV-------------NVTPDAFLGLSNL--THLSLKYNNLTEVPRQLPPSLEYLLLSYNL----I 232

  Fly   220 VSFGNPLLRELQQLRNL----------------------SLALIHP--FHE---------RDK-- 249
            |..|...|..|..||.|                      ||.| ||  ||.         :|.  
  Rat   233 VKLGPEDLANLTSLRVLDVGGNCRRCDHAPDLCTECRQKSLDL-HPQTFHHLSHLEGLVLKDSSL 296

  Fly   250 -QLQPHFFGSMTNL-----------EEVRLASATSSVNR----------------------SMFK 280
             .|...:|..:.||           |.:...||..::.|                      |.||
  Rat   297 HSLNSKWFQGLVNLSVLDLSENFLYESINKTSAFQNLTRLRKLDLSFNYCKKVSFARLHLASSFK 361

  Fly   281 GTNKLQLIKMNG-------NDDLMELPG----------EIFLDQVNLK----------------- 311
            ....||.:.|||       .:.|..|.|          ..|::|..|.                 
  Rat   362 SLVSLQELNMNGIFFRLLNKNTLRWLAGLPKLHTLHLQMNFINQAQLSVFSTFRALRFVDLSNNR 426

  Fly   312 --------------------------------------------------TLDLSCNAIVTLHED 326
                                                              |:|||.|.:||:..:
  Rat   427 ISGPPTLSRVAPEKADEAEKGVPWPASLTPALPSTPVSKNFMVRCKNLRFTMDLSRNNLVTIKPE 491

  Fly   327 VFKGLGNLTLLDLSKNRLTN-LSSTIFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLNYIEM-VN 389
            :|..|.:|..|.||.|.:.. ::.:.|.|||:|.||.|:.|.|.......|.::..|..::: .|
  Rat   492 MFVNLSHLQCLSLSHNCIAQAVNGSQFLPLTNLKVLDLSYNKLDLYHSKSFSELPQLQALDLSYN 556

  Fly   390 TQFYGA-------TLLMNYEAV----VCTNDEACQYKSAEWQCDPRCICWVQRSVGSL------- 436
            :|.:..       :.|.|...:    :..||...:..|..:......:.:....||.:       
  Rat   557 SQPFSMQGIGHNFSFLANLSRLQNLSLAHNDIHSRVSSRLYSTSVEYLDFSGNGVGRMWDEEDLY 621

  Fly   437 ---IVDCRGTSLEELPDLPRTTLLSTVLKVGN-----NSLTSLPTVSEHSGYANVSGLF------ 487
               ..|.|  ||..| ||.:..|  .:|:..|     .|||.|.....|..:.|.|.|.      
  Rat   622 LYFFQDLR--SLIHL-DLSQNKL--HILRPQNLNYLPKSLTKLSFRDNHLSFFNWSSLAFLPNLR 681

  Fly   488 ---LSDNNLTSLGSGDQLPDN--LTHLDVRGNQIQSLSDEFLLF---LQEPN------------- 531
               |:.|.|.:|.:| .||:.  |..|||..|.|..:...|...   |:|.|             
  Rat   682 DLDLAGNLLKALTNG-TLPNGTLLQKLDVSSNSIVFVVPAFFALAVELKEVNLSHNILKTVDRSW 745

  Fly   532 ------NTMTLSLSGNPITCGCES--LSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAF---- 584
                  |...|.:|.||:.|.|.:  :.||..|:|   :|..:|:.|.....:..|....|    
  Rat   746 FGPIVMNLTVLDVSSNPLHCACGAPFVDLLLEVQT---KVPGLANGVKCGSPRQLQGRSIFAQDL 807

  Fly   585 ELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQEL---KIWLYNNNLCLWWV--------SEEEL 638
            .||...||...| .|..::.:.:.||..|:  |.|   .:| |..:|||.|:        |.:.|
  Rat   808 RLCLDDVLSRDC-FGLSLLAVAVGTVLPLL--QHLCGWDVW-YCFHLCLAWLPLLTRGRRSAQAL 868

  Fly   639 DKDKTYDAFISY----SHKDEELISKLLPKLES--GPHPFRLCLHDRDWLVGDCIPEQIVRTVDD 697
                .||||:.:    |...:.:.::|..:||.  |....||||.|||||.|..:.|.:..::..
  Rat   869 ----PYDAFVVFDKAQSAVADWVYNELRVRLEERRGRRALRLCLEDRDWLPGQTLFENLWASIYG 929

  Fly   698 SKRVIIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYLKLNTYL 762
            |::.:.||:.....|...|..|.:|.|..|:|::..:::::.|...|.:.. ..||..|...:.|
  Rat   930 SRKTLFVLAHTDKVSGLLRTSFLLAQQRLLEDRKDVVVLVILRPDAHRSRY-VRLRQRLCRQSVL 993

  Fly   763 KW-----GDPLFWSKLYYAMP------HNRRVLKG 786
            .|     |...||::|..|:.      :||...:|
  Rat   994 FWPHQPNGQGSFWAQLSTALTRDNHHFYNRNFCRG 1028

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TehaoNP_001285901.1 leucine-rich repeat 185..207 CDD:275380 7/24 (29%)
leucine-rich repeat 209..232 CDD:275380 6/22 (27%)
leucine-rich repeat 233..261 CDD:275380 13/63 (21%)
LRR_RI <261..370 CDD:238064 44/226 (19%)
leucine-rich repeat 262..284 CDD:275380 8/54 (15%)
leucine-rich repeat 285..309 CDD:275380 10/40 (25%)
LRR_8 309..368 CDD:290566 24/126 (19%)
leucine-rich repeat 310..333 CDD:275380 10/89 (11%)
leucine-rich repeat 334..357 CDD:275380 8/23 (35%)
leucine-rich repeat 358..381 CDD:275380 7/22 (32%)
leucine-rich repeat 445..482 CDD:275380 12/41 (29%)
LRR_8 459..516 CDD:290566 22/72 (31%)
leucine-rich repeat 483..505 CDD:275380 9/30 (30%)
LRR_4 486..521 CDD:289563 14/45 (31%)
TIR 643..779 CDD:214587 42/152 (28%)
Tlr9NP_937764.1 leucine-rich repeat 43..64 CDD:275380
LRR_8 63..135 CDD:290566 11/46 (24%)
leucine-rich repeat 65..88 CDD:275380
leucine-rich repeat 89..124 CDD:275380 7/31 (23%)
LRR_RI 123..373 CDD:238064 61/304 (20%)
leucine-rich repeat 125..144 CDD:275380 7/26 (27%)
LRR_8 143..211 CDD:290566 20/109 (18%)
leucine-rich repeat 145..168 CDD:275380 3/26 (12%)
leucine-rich repeat 169..200 CDD:275380 11/66 (17%)
LRR_8 199..254 CDD:290566 16/60 (27%)
leucine-rich repeat 201..221 CDD:275380 7/21 (33%)
leucine-rich repeat 222..245 CDD:275380 6/26 (23%)
leucine-rich repeat 246..285 CDD:275380 10/39 (26%)
LRR_8 284..344 CDD:290566 9/59 (15%)
leucine-rich repeat 286..309 CDD:275380 3/22 (14%)
LRR_RI 310..556 CDD:238064 45/245 (18%)
leucine-rich repeat 310..335 CDD:275380 4/24 (17%)
leucine-rich repeat 336..365 CDD:275380 3/28 (11%)
leucine-rich repeat 393..416 CDD:275380 3/22 (14%)
leucine-rich repeat 477..498 CDD:275380 9/20 (45%)
LRR_RI <490..692 CDD:238064 49/206 (24%)
LRR_8 497..556 CDD:290566 17/58 (29%)
leucine-rich repeat 499..523 CDD:275380 8/23 (35%)
leucine-rich repeat 524..547 CDD:275380 7/22 (32%)
leucine-rich repeat 548..577 CDD:275380 5/28 (18%)
leucine-rich repeat 578..630 CDD:275380 7/53 (13%)
leucine-rich repeat 601..618 CDD:275380 2/16 (13%)
LRR_8 629..690 CDD:290566 19/65 (29%)
leucine-rich repeat 631..655 CDD:275380 7/26 (27%)
leucine-rich repeat 656..679 CDD:275380 7/22 (32%)
leucine-rich repeat 680..703 CDD:275380 7/23 (30%)
LRR_8 704..763 CDD:290566 14/58 (24%)
leucine-rich repeat 704..727 CDD:275380 7/22 (32%)
leucine-rich repeat 728..746 CDD:275380 3/17 (18%)
leucine-rich repeat 753..774 CDD:275380 6/20 (30%)
TIR_2 870..1013 CDD:304906 41/143 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4641
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D147327at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

Return to query results.
Submit another query.