Protein Alignment Tehao and Toll-9

DIOPT Version :10

• Sequence 1: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: XP_565221.3
• Gene: Toll-9 / 3290281
• VectorBaseID: AGAMI1_015050
• Length: 817
• Species: Anopheles gambiae
• Alignment Length: 719
• Identity: 157/719 - (21%)
• Similarity: 266/719 - (36%)
• Gaps: 226/719 - (31%)

  Fly   188 LHLSV---NVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIHPFHERDK 249
            ||||:   .:|.:|                         :|.|::.|.:|.|||:
Mosquito   185 LHLSIARNELTLVP-------------------------SPTLKKFQNVRLLSLS---------- 214

  Fly   250 QLQPHFFGSMTN--LEEVRLASATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKT 312
               .:||...:|  .|..||...|            ||:::.|. |..|..|| |.|...|||:.
Mosquito   215 ---GNFFTEFSNDTAEHNRLPLLT------------KLRVLDMR-NCSLRTLP-EAFFRNVNLEY 262

  Fly   313 LDLSCNAIVTLHEDVFKGLGNLTLLDLS--------KNRLTNLSSTIFAPLTSLNVLRLNKNSLT 369
            |.||.|.|.||..::|..|.:|..||||        :.|:.|....:.|.:.
Mosquito   263 LFLSHNRITTLPAEIFYPLRSLLHLDLSNMDTRRTGEERIENPFMKLIAGVD------------- 314

  Fly   370 AMSPSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCIC------- 427
             :...:|..::||.::::.||:       :.|:|.:.       .:|.:|:......|
Mosquito   315 -LHQDIFFPLISLVFLDLSNTR-------LEYQAFIA-------LRSVQWRVQYVSYCNIGLPAI 364

  Fly   428 ----WVQRSVGSLIVDCRGTSLEELPDLPRTTLLST------------------------VLKVG 464
                :|.:.:..|.:.......:.|.....|.|..:                        ||.:.
Mosquito   365 VDYLFVSKKIAMLDISYNVGVAQSLHSASFTLLADSLEVLYFKDSMVQQLNWLVPLQRLRVLNLR 429

  Fly   465 NNSLTSLPTVSEHSGYANVSGLFLSDNNLTSLGSGDQ----LPDNLTHLDVRGNQIQSLSDEFLL 525
            .|.|..|    :...:||::.|...|.:...:.:.:|    ....|..:::|.|.|..|:.:
Mosquito   430 GNILRML----QRESFANLTHLEQLDLSYNYISAWNQQILTTTTALQSVNLRNNSIVILTTD--- 487

  Fly   526 FLQEPNNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIAD---------IV------CTKQK 575
            .|.:.:....:.|.||.|.|.|..:.   |:|.......|:|.         ||      ....|
Mosquito   488 MLYDFSRLSAMGLGGNTIQCSCNYVK---FLRNILHNRTDVAGAYTISAEPLIVGRRGSGTISNK 549

  Fly   576 KSFQQMEAFE------LCPSYV------------------------------------------- 591
            .|.|.::.|:      ||.::.
Mosquito   550 LSLQHVQLFDYEESEYLCMNFTSNQKLDPLELQDCMIPEDELINSDIPEEGEDEPAHAKNHTLVY 614

  Fly   592 LLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSEEELDKDKT---------YDAF 647
            :|:|..|..|::.  .:.:||..|..:....:..|:..|.:.::|:|..||:         ||.|
Mosquito   615 ILVSVAVSFLILT--GVGLFYYWFHIKYFFKIMKNSAVLSFFNDEKLYLDKSGLLKEADFHYDVF 677

  Fly   648 ISYSHKDEE-LISKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHFID 711
            :|||:.|.. ::..|||.:| |.....||||:||:.||..|.|.|:..:|.|:.:::::|:.|:.
Mosquito   678 VSYSNADRSWVLDHLLPNME-GVSQINLCLHERDFEVGYGILENIISCMDRSRCLMLIVSESFLL 741

  Fly   712 SVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSELRAYLKLNTYLKW------GDPLFW 770
            |.|.:.|..:|....|:..|..:|::|..::.... ....|...||..||:||      ...|||
Mosquito   742 SHWCQFEMHLAQHRLLETCRDELILVLLEDIPRRK-CPKTLSYLLKTKTYIKWPTKSVHEQALFW 805

  Fly   771 SKLY 774
            .:|:
Mosquito   806 KRLH 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_477438.1	LRR	184..>541	CDD:443914	81/404 (20%)
		leucine-rich repeat	185..207	CDD:275380	6/21 (29%)
		leucine-rich repeat	209..232	CDD:275380	2/22 (9%)
		leucine-rich repeat	233..261	CDD:275380	6/27 (22%)
		leucine-rich repeat	262..284	CDD:275380	4/21 (19%)
		leucine-rich repeat	285..309	CDD:275380	8/23 (35%)
		leucine-rich repeat	310..333	CDD:275380	10/22 (45%)
		leucine-rich repeat	334..357	CDD:275380	8/30 (27%)
		leucine-rich repeat	358..381	CDD:275380	1/22 (5%)
		leucine-rich repeat	445..482	CDD:275380	8/60 (13%)
		leucine-rich repeat	483..505	CDD:275380	3/25 (12%)
		TIR	643..779	CDD:214587	46/148 (31%)
Toll-9	XP_565221.3	None