Protein Alignment Tehao and Tlr6

DIOPT Version :10

• Sequence 1: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: NP_997487.2
• Gene: Tlr6 / 305353
• RGDID: 1303030
• Length: 806
• Species: Rattus norvegicus
• Alignment Length: 797
• Identity: 176/797 - (22%)
• Similarity: 295/797 - (37%)
• Gaps: 249/797 - (31%)

  Fly   166 KFFSHVPELQESIFHGFDTLRDLHLSVNVTTLPGNMLSTVN-------GTLKTLTIESPGI--VS 221
            |..:|||             :||..|....:|..|.:|.:.       ..|:.|.:....|  :.
  Rat    52 KNLTHVP-------------KDLSPSTKSLSLSQNSISDLQMSDISFLSELRVLRLSHNRIRRLD 103

  Fly   222 FGNPLL-RELQ-------QLRNLSLA-LIHPFH----ERDKQLQPHF--FGSMTNLEEVRLASA- 270
            ||..|| |:|:       ||:|:|.. :::..|    ..|.::.|.:  ||::..|..:.|::|
  Rat   104 FGVFLLNRDLEYLDVSHNQLQNISCCPMVNLKHLDLSFNDFEVLPVYKEFGNLMKLSFLGLSAAK 168

  Fly   271 ------------------TSSVNRSMFKG-TNKLQLIKMNGNDDLMEL---PGEIFLDQV----- 308
                              ...||..:..| |..||:    .|.:::.|   |..:|..||
  Rat   169 FRQLDLLPISHLHLSCVLLDLVNYQIKDGETESLQV----PNTNVLHLVFHPNSLFSVQVNISVN 229

  Fly   309 --------NLKTLDLSCNAIVTLHEDVFKG--LGNLTLLDLSKN-------------------RL 344
                    |:|..|.:|.:::....::.:|  |.||||..:..|                   .:
  Rat   230 ALGCLQLSNIKLNDKNCQSLIIFLSELTRGPTLLNLTLQHIETNWKCFVRLLQFLWPRPVEYLNI 294

  Fly   345 TNLSST----------IFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLN----------YIEMVN 389
            .||:.|          :...|.||.:..:.......:..:::.....:|          :|.||.
  Rat   295 YNLTITESISRETFIYVETVLKSLKIEHVTNQVFLFVKDALYSVFAEMNIRMLTLSDTPFIHMVC 359

  Fly   390 TQFYGATLLMNYEAVVCTNDEACQYKSAEWQCDPRCICWVQRSVGSLIVDCRG------------ 442
            .:|......:|:...|.| |...|.            |...:.:.:||:...|
  Rat   360 PEFPSTFAFLNFTQNVFT-DSIFQG------------CSTLKRLETLILQRNGLKNLFKVALMTK 411

  Fly   443 --TSLEELPDLPRTTLLS-----------------------------------TVLKVGNNSLTS 470
              :|||.| |:...:|.|                                   .||.:.||.:.|
  Rat   412 TMSSLETL-DVSLNSLNSHVYDRTCAWAESIRVLNLSSNVLSDSVFRCLPPKVKVLDLHNNRIVS 475

  Fly   471 LPTVSEH---SGYANVSGLFLSDNNLTSLGSGDQLPDNLTHLDVRGNQIQSLSDEFLLFLQEPNN 532
            :|....|   ....||:..||:|  |...|:.    .:|:.|.:..|.:...|.:   |.|...|
  Rat   476 IPKDVTHLQALQELNVASNFLTD--LPGCGAF----SSLSVLVIDHNSVSHPSSD---FFQSCQN 531

  Fly   533 TMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQ------MEAFELCP--S 589
            ..:::...||..|.||   |..||:...|..|::.:......:..:..      ::.|.:.|  .
  Rat   532 IRSITAGNNPFRCTCE---LREFVKNIGQASREVVEGWPDSYRCDYPDSIKGTPLQDFHMSPLSC 593

  Fly   590 YVLLISCVVGGLVIV-------ICLLTVFYLMFQQELKIWLYNNNLCLW-W---------VSEEE 637
            ..:|::..:|..:::       :||    |......|::        || |         :..||
  Rat   594 DTILLTVTIGATLLLLAAIGASLCL----YFDLPWYLRM--------LWQWTQTRHRARNIPLEE 646

  Fly   638 LDKDKTYDAFISYSHKDEELI-SKLLPKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRV 701
            |.::..:.||:|||..|...: ::|||.||.  ...|:|||:|:::.|..|.|.|:..::.|.:.
  Rat   647 LQRNLQFHAFVSYSEHDSAWVKNELLPNLEK--DDIRVCLHERNFVPGKSIVENIIHFIEKSYKS 709

  Fly   702 IIVLSQHFIDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDS---ELRAYLKLNTYLK 763
            |.|||.|||.|.|...|...|:.....:....:|:||...:: .|.|.|   :|||.:...|||:
  Rat   710 IFVLSPHFIQSEWCHYELYFAHHNLFHEGSDNLILILLEPIQ-QNNIPSRYHKLRALMAQRTYLE 773

  Fly   764 WGDP-------LFWSKL 773
            |  |       |||:.|
  Rat   774 W--PIEKGKRGLFWANL 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_477438.1	LRR	184..>541	CDD:443914	98/509 (19%)
		leucine-rich repeat	185..207	CDD:275380	6/28 (21%)
		leucine-rich repeat	209..232	CDD:275380	9/32 (28%)
		leucine-rich repeat	233..261	CDD:275380	8/34 (24%)
		leucine-rich repeat	262..284	CDD:275380	7/41 (17%)
		leucine-rich repeat	285..309	CDD:275380	8/39 (21%)
		leucine-rich repeat	310..333	CDD:275380	5/24 (21%)
		leucine-rich repeat	334..357	CDD:275380	8/51 (16%)
		leucine-rich repeat	358..381	CDD:275380	1/22 (5%)
		leucine-rich repeat	445..482	CDD:275380	13/74 (18%)
		leucine-rich repeat	483..505	CDD:275380	6/21 (29%)
		TIR	643..779	CDD:214587	50/142 (35%)
Tlr6	NP_997487.2	None