Protein Alignment Tehao and Toll-7

DIOPT Version :10

• Sequence 1: NP_477438.1
• Gene: Tehao / 34761
• FlyBaseID: FBgn0026760
• Length: 795
• Species: Drosophila melanogaster
• Sequence 2: XP_320221.5
• Gene: Toll-7 / 1280374
• VectorBaseID: AGAMI1_009495
• Length: 1328
• Species: Anopheles gambiae
• Alignment Length: 924
• Identity: 208/924 - (22%)
• Similarity: 349/924 - (37%)
• Gaps: 268/924 - (29%)

  Fly    10 LFFALLVLRSATGQIIPLPTFCLGLSPQCTCAAEGNVVRFHCPDEYAMLLEVSEPGASLYMSYYA 74
            ||..|.||...|            |:.......|.||.| :|.|    |.|:......|....||
Mosquito   389 LFNGLFVLSKLT------------LNNNLISIVEPNVFR-NCSD----LKELDLSSNQLTEVPYA 436

  Fly    75 STELQWLPRFNI--SSLVKIEFDAYIFWPEKFLSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLN 137
            ..:|..|...::  :.:.:||...:        ::|.:..|::.:
Mosquito   437 IRDLSMLRALDLGENQIARIENGTF--------ANLNQLTGLRLI-------------------- 473

  Fly   138 SGNGYMETSQPENITTWHFGSVPGLKKFKFF-SHVPELQESIFHGFDTLRDLHLSVNVTTLPGNM 201
                   .:|.||:|...|..:|.|...... :.|..::...|       |.:|.:....|.||.
Mosquito   474 -------DNQIENVTVGMFADLPRLSVLNLAKNRVQNIERGSF-------DRNLDIEAIRLDGNF 524

  Fly   202 LSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLALIH---------PFHERDKQLQPHFFG 257
            |:.:||...||.                  .|..|:||..|         |.:.:...:..::..
Mosquito   525 LTDINGIFATLA------------------SLLWLNLAENHLVWFDYAFIPSNLKWLDIHGNYIE 571

  Fly   258 SMTNL----EEVRLASATSSVNRSMFKG----TNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLD 314
            |:.|.    ||:::.:..:|.||....|    .|.::|:.:|.| .:..:....|:|:|||..:|
Mosquito   572 SLGNYYKLQEEIKVKTLDASHNRLTDLGPMNVPNSVELLFVNDN-HIGTIHANTFIDKVNLARVD 635

  Fly   315 LSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSSTIFAPL-------------TSLNVLRLNKN 366
            |..||              |..|.|.:.|:.....|...||             .|:..::...|
Mosquito   636 LYANA--------------LKKLQLHQLRVAPAPPTTERPLPEFYLGGNPFECDCSMEWMQRVNN 686

  Fly   367 SLTAMSPSVFQDVVSLNYIEMVNTQFYGATL-----------LMNYEA-----VVCTNDEACQYK 415
            ..|...|.    ::.|..:|.:.....|:.:           |..||.     ..|.:.:||
Mosquito   687 LTTRQHPK----IMDLPNVECIMPHARGSPIRPIVSLQPKDFLCRYETHCFALCHCCDFDAC--- 744

  Fly   416 SAEWQCDPRCICWVQRSVGSLIVDC--RGTSL--------------------EELPDLPRTTLL- 457
            ..|..|...|.|:..::.|:.:|||  :|.:.                    .::|:|.....:
Mosquito   745 DCEMTCPSNCTCYHDQTWGTNVVDCGNQGAAAAAAGGLRPVPMDATEVYLDGNDIPELQHHVFIG 809

  Fly   458 -----------STVLKVGNNSLTSLPTVS---------------EHSGYANVSGLFLSDNNLTSL 496
                       |.:..:.|.:...|..:.               |....|.:..|:|.:|.|.|:
Mosquito   810 RKNLKVLYANASRIATIQNRTFAGLTALQALHLEDNALQRIHGYEFENLALLRELYLQNNGLQSI 874

  Fly   497 GSGDQLP-DNLTHLDVRGNQIQSLSDEFLLFLQEPNNTM----TLSLSGNPITCGCESL-SLLFF 555
            .:|...| .:|..|.:.||::.::.   |..||.....:    :|||..||.:|.|..| .|..|
Mosquito   875 ANGSFAPLYSLRVLRLDGNRLVTMP---LFQLQAAQGNLQALQSLSLGRNPWSCRCRFLPELTAF 936

  Fly   556 VRTNPQRVRDIADIVC----TKQKKSFQQMEAFE-------------LCPSYVLLISCVVGGLVI 603
            |..|...|:|..|:.|    ..::..|....|..             |..:|::|::..    |:
Mosquito   937 VADNAVIVQDPQDVYCADDGVHRELDFNVSAACSDFYAGRSVLPGDGLPETYIMLMALA----VV 997

  Fly   604 VICLLTVFYLM--FQQELKIWLYNNNLCLWWVSEEELDKDKTYDAFISYSHKDEELISK-LLPKL 665
            ::|||.:..||  |::.|:.||::......:....| |.:|.|||.:.||.||.||::: :..:|
Mosquito   998 LVCLLLLAVLMFVFREPLRFWLFSRYGVRVFGPRCE-DSEKLYDAILLYSAKDAELVARSIAGEL 1061

  Fly   666 ESGPHPFRLCLHDRDWLVGDCIPE-----QIVRTVDDSKRVIIVLSQHFIDSVWARMEFRIAYQA 725
            |:|..|.||||..||      :||     |::.....|:|::::||::|:.:.|:|.|.|.|...
Mosquito  1062 ENGRPPLRLCLQHRD------LPEDASHLQLLEASRASRRIVVLLSRNFLQTEWSRCELRRAVHD 1120

  Fly   726 TLQDKRKRIIIILYRELEHMNGI------DSELRAYLKLNTY--LKWGDPLFWSKLYYAMP---- 778
            .|:.:..:::::     |...|:      |.||..|||..|.  ::.||..||.||.||:|
Mosquito  1121 ALRGRPHKLVVV-----EEGGGVLLEAENDVELVPYLKTTTVTRVRRGDRHFWEKLRYALPVEAP 1180

  Fly   779 ---------HNRRV 783
                     |:.||
Mosquito  1181 YRGNNYTIDHHERV 1194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_477438.1	LRR	184..>541	CDD:443914	90/456 (20%)
		leucine-rich repeat	185..207	CDD:275380	6/21 (29%)
		leucine-rich repeat	209..232	CDD:275380	2/22 (9%)
		leucine-rich repeat	233..261	CDD:275380	7/36 (19%)
		leucine-rich repeat	262..284	CDD:275380	6/29 (21%)
		leucine-rich repeat	285..309	CDD:275380	5/23 (22%)
		leucine-rich repeat	310..333	CDD:275380	5/22 (23%)
		leucine-rich repeat	334..357	CDD:275380	7/35 (20%)
		leucine-rich repeat	358..381	CDD:275380	3/22 (14%)
		leucine-rich repeat	445..482	CDD:275380	6/83 (7%)
		leucine-rich repeat	483..505	CDD:275380	7/22 (32%)
		TIR	643..779	CDD:214587	51/162 (31%)
Toll-7	XP_320221.5	None