DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Tehao and LOC100485927

DIOPT Version :9

Sequence 1:	NP_001285901.1	Gene:	Tehao / 34761	FlyBaseID:	FBgn0026760	Length:	795	Species:	Drosophila melanogaster
Sequence 2:	XP_017946494.1	Gene:	LOC100485927 / 100485927	-ID:	-	Length:	782	Species:	Xenopus tropicalis

Alignment Length:	796	Identity:	167/796 - (20%)
Similarity:	290/796 - (36%)	Gaps:	265/796 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 SVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQLRNLSLA--LIHPFHERDKQLQP 253
            |::...:|..:...|.|    |.:.|..|.......|:...||:.|.|.  .||..:  |...||
Frog    36 SMHWEAIPSGLPRDVRG----LNLSSNAIQIVTETDLKPYDQLQTLLLQYNAIHTIN--DGSFQP 94

  Fly   254 HFFGSMTNLEEVRLA----SATSSVNRSMFKGTNKLQLIKMNGNDDLMELPGEIFLDQVNLKTLD 314
                 :.||||:.|:    ...|||   .|:..|||:.:.:.||..:......:|....:|.:|.
Frog    95 -----LGNLEELDLSYNNLVLLSSV---WFRNLNKLKHLNLLGNQYITLGNDSLFASLSSLSSLQ 151

  Fly   315 LSCNAIVTLHEDVFKGLGNLTLLDLSKNRLTNLSSTIFAPLTSL--NVLRLNKNSLTAMSPSVFQ 377
            ........:.:..|:||..|..|:::..:||.........:..:  .:||:|   ||.: |::.:
Frog   152 FGNQNFDAIQKQSFEGLERLNTLEINAAQLTLYEEGSLGRMKQIYHTILRVN---LTLL-PALLK 212

  Fly   378 DVV-SLNYIEMVNTQFYGATLLMNYEAVV-----------CTNDEACQYKSAEWQCDPRCICWVQ 430
            |:| |:..:|:.:|:|.....:..:|.:.           ||..:...|:..|       |....
Frog   213 DLVHSVTLLEITDTEFSTPADMQAFEVLAYTSVKQFIFRNCTIVDVSGYRFVE-------IIQTY 270

  Fly   431 RSVGSLIV-DCR--GTSLEELPDLPRTT------------------------------------- 455
            |::..::: :||  |..| :.|:|.|||
Frog   271 RNITDVVMKNCRLLGRGL-DCPNLKRTTSSVTTIIINNIEVSLYYIFSDLSSLHQIIPQFTYVTV 334

  Fly   456 ---------------------------------LLSTV--------------LKVGNNSLTSLPT 473
                                             |.|:|              |.|..|.|||:|.
Frog   335 TDSPVYLIPCQFSQSFTSLQYLDVSGGKLDNTYLGSSVCYHEGGGACPKLQTLNVSRNLLTSVPK 399

  Fly   474 VSEH-SGYANVSGLFLSDNNLTSLGSGD-QLPDNLTHLDVRGNQIQ-------------SLSDEF 523
            |::. ||...::.|.:|.|..:.|.:.. |.|.||.:|::..|||.             .:|..:
Frog   400 VAQFLSGLNYLTNLDISQNKFSELSTSKCQWPKNLKYLNISNNQINIITTCIPPTLQILDVSSNY 464

  Fly   524 L--LFLQEPNNT---------------------MTLSLSGNPIT--------------------- 544
            |  ..::.||.|                     :.||:|.|.:.
Frog   465 LTVFAIEMPNLTELYISNNRLSKLPEGMYFTSLVLLSISRNDLNGFGQSDLELFSNRTILDARAN 529

  Fly   545 ---CGCESLSLLFFVRTN---------------PQRVRDI-------ADIVCTKQKKSFQQMEAF 584
               |.|:.|.   |:|:|               |..|:|:       ..:||.|
Frog   530 NYKCSCQFLD---FIRSNTAVLVGWPDNYKCASPASVKDVQIQDANLPPLVCHK----------- 580

  Fly   585 ELCPSYVLLISCVVGGLVIVICLLTVFYLMFQQELKIWLYNNNLCLWWVSE----EELDKDKTYD 645
                :.::.:||     :::|.|:.....:......:| |......|..::    :..|::..:|
Frog   581 ----TLIVTLSC-----ILLIALVAAIVALCHFLHVVW-YAKMTWAWLKAKRKPLKNCDREICFD 635

  Fly   646 AFISYSHKDEELISKLL-PKLESGPHPFRLCLHDRDWLVGDCIPEQIVRTVDDSKRVIIVLSQHF 709
            .|:|||.:|.|.:..:: ||||:.....:||||.||::.|..|.:.|:..::.|.:.:.|||:||
Frog   636 GFVSYSERDSEWVENMMVPKLENATLAMKLCLHKRDFVPGKWIIDNIIDAMEKSYKTVFVLSEHF 700

  Fly   710 IDSVWARMEFRIAYQATLQDKRKRIIIILYRELEHMNGIDSE--------LRAYLKLNTYLKW-- 764
            :.|.|.:.|...::.....:.....|:||      ::.|:.|        ||..:...|||:|
Frog   701 VRSEWCKYELEFSHFRLFDENNDSAILIL------LDPIEKETVPKRFCKLRKLMNTKTYLEWPT 759

  Fly   765 ---GDPLFWSKLYYAM 777
               ...:||..|..|:
Frog   760 DEEQQEVFWDNLKTAL 775

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tehao	NP_001285901.1	leucine-rich repeat	185..207	CDD:275380	3/15 (20%)
		leucine-rich repeat	209..232	CDD:275380	4/22 (18%)
		leucine-rich repeat	233..261	CDD:275380	8/29 (28%)
		LRR_RI	<261..370	CDD:238064	28/114 (25%)
		leucine-rich repeat	262..284	CDD:275380	8/25 (32%)
		leucine-rich repeat	285..309	CDD:275380	4/23 (17%)
		LRR_8	309..368	CDD:290566	12/60 (20%)
		leucine-rich repeat	310..333	CDD:275380	5/22 (23%)
		leucine-rich repeat	334..357	CDD:275380	4/22 (18%)
		leucine-rich repeat	358..381	CDD:275380	8/25 (32%)
		leucine-rich repeat	445..482	CDD:275380	19/121 (16%)
		LRR_8	459..516	CDD:290566	21/72 (29%)
		leucine-rich repeat	483..505	CDD:275380	6/22 (27%)
		LRR_4	486..521	CDD:289563	12/48 (25%)
		TIR	643..779	CDD:214587	44/149 (30%)
LOC100485927	XP_017946494.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D147327at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010