DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10859 and CG13074

DIOPT Version :9

Sequence 1:	NP_001285898.1	Gene:	CG10859 / 34756	FlyBaseID:	FBgn0032520	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_648835.1	Gene:	CG13074 / 39760	FlyBaseID:	FBgn0036567	Length:	451	Species:	Drosophila melanogaster

Alignment Length:	267	Identity:	54/267 - (20%)
Similarity:	85/267 - (31%)	Gaps:	105/267 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   161 HDLWIPSRRLMTCEWLNNDPNQFLLFYSNRMSL--TPDYTKQLNTLPDFGNDNPHAFYIWNLDDA 223
            ||.|        ||.::   .|..||...|||:  ...|| :..|||
  Fly   150 HDDW--------CEHVD---QQLKLFVPQRMSVGNLVIYT-EAKTLP------------------ 184

  Fly   224 TRPAAHYDSRRVVRVAKVCLR-------DESYMVGGLQEGQVGFWLTENQGGPKSMCPLEACHRE 281
                           .|.|||       :::...|...:|::..||.|...|..|...::..:..
  Fly   185 ---------------LKSCLRSLCTNPFNKTMFAGSTMDGELFIWLYEQARGSDSSVDIKQLYSV 234

  Fly   282 ATT-----AICWVHSKLNTEFYSGSLDGSIKYWDTRDLLMPVHEVLAEPDPQTVQNRQDAHGVTF 341
            ::|     |:.|....|....::   :||::.||.                    :||.|
  Fly   235 SSTQGAAVALDWPREHLLLACFA---NGSVRQWDL--------------------SRQMA----- 271

  Fly   342 LEFEYTIPVRF------IFCTDMGYLFVGNRKG-------TTPQDTIVAAYQLFAGPIRCVMRNP 393
            |::|||:|...      :....:....||...|       |..|...:...:|.|     :.|:.
  Fly   272 LDWEYTLPATVSSEPTAMVTLGLDDFVVGTNDGGVYRCWNTGRQTAAIKQIKLLA-----LRRHR 331

  Fly   394 FFVKNFL 400
            |.|...|
  Fly   332 FMVSTLL 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10859	NP_001285898.1	WD40	<245..310	CDD:295369	13/69 (19%)
		WD40	261..>512	CDD:225201	32/158 (20%)
		WD40	279..492	CDD:295369	27/140 (19%)
		WD40 repeat	284..332	CDD:293791	8/52 (15%)
		WD40 repeat	386..422	CDD:293791	4/15 (27%)
		WD40 repeat	429..454	CDD:293791
CG13074	NP_648835.1	WD40 repeat	189..234	CDD:293791	9/44 (20%)
CG13074	NP_648835.1	WD40 repeat	242..275	CDD:293791	11/60 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12442
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100