DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10859 and dnai4

DIOPT Version :9

Sequence 1:	NP_001285898.1	Gene:	CG10859 / 34756	FlyBaseID:	FBgn0032520	Length:	627	Species:	Drosophila melanogaster
Sequence 2:	NP_001106504.1	Gene:	dnai4 / 100127694	XenbaseID:	XB-GENE-5890871	Length:	795	Species:	Xenopus tropicalis

Alignment Length:	462	Identity:	80/462 - (17%)
Similarity:	151/462 - (32%)	Gaps:	150/462 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 VNQLMHAAMDISSANNAVNI-------------YEDF-FVDLPEDLGRGISMKIAARGTHVFHDL 163
            :|:|...|.|::..:|..:|             |..| |.:....:....|:|.......:||
Frog   419 LNRLWSFACDVTKGHNVSSISWNKKNSDLLAVGYGQFGFTEQKGGMACCWSLKNIMWPERIFH-- 481

  Fly   164 WIPSRRLMTCE-------WLNNDPNQFLL-FYSNRMSLTPDYTKQLN----TLPDFGNDNPHAFY 216
                     ||       :....||...: .|:..:::   |..|.|    .|....|.|.|...
Frog   482 ---------CECGVTAVDFSAVHPNLLAVGMYNGTVAI---YNVQNNEDFPVLDSSDNPNKHTSP 534

  Fly   217 IWNLDDATRPAAHYDSRRVVRVAKVCLRDESYMVGGLQEGQVGFWLTENQGGPKSMCPLEACHRE 281
            :|.|.                                       |:..::|.      |.....|
Frog   535 VWQLK---------------------------------------WIEHDRGN------LGDDKGE 554

  Fly   282 ATTAICWVHSKLNTEFYSGSLDGSIKYW------DTRDLLMPVHEVLAEPDPQTVQNRQDAHGVT 340
            ...::|              .||.|..|      |..| ||.:....:|...:: .|.::..|..
Frog   555 ILVSVC--------------ADGRITRWHIRKGLDCND-LMKLKRTGSEKSKKS-SNEKEKKGEA 603

  Fly   341 FLE-------FEYTIPVRFIFCTDMGYLFVGNRKG------TTPQDTIVAAYQLFAGPIRCVMRN 392
            |:.       |:: :|      .|......|..:|      .:..:..:..|:...||:..:..:
Frog   604 FISRQAPGMCFDF-LP------KDSNIYLAGTEEGHIHKCSCSYNEQFLDTYRGHKGPVYKIAWS 661

  Fly   393 PFFVKNFL-VVGDWRVRIWSEEVKNCPSTFYFRRPNQLLSGAWSTGRCSLF-CIGDNMGNLEFWD 455
            ||....|| ...||.:.:|.::|.: |...:....|.:....||.....:| .:.:|  .:|.||
Frog   662 PFCPDVFLSCSADWCIHLWQQDVLS-PILTFSNTTNAVYDIMWSPSSALMFGAVTEN--RVEIWD 723

  Fly   456 LLMSHKRPILTIKYKYAV--THLVFKPDGTMLTVSLANGDCLMLRLEEG------MRSATNKEKS 512
            |..|...|::..:....|  |.::|          ..|.:|:::...:|      :|:.::.:.|
Frog   724 LGTSTIDPLIVNEANPGVKLTSILF----------AKNTNCVLIGDSDGQVNVYELRNVSSSKDS 778

  Fly   513 LMMSMFE 519
            .:.::::
Frog   779 EVNALYD 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10859	NP_001285898.1	WD40	<245..310	CDD:295369	9/70 (13%)
		WD40	261..>512	CDD:225201	52/279 (19%)
		WD40	279..492	CDD:295369	45/235 (19%)
		WD40 repeat	284..332	CDD:293791	10/53 (19%)
		WD40 repeat	386..422	CDD:293791	9/36 (25%)
		WD40 repeat	429..454	CDD:293791	5/25 (20%)
dnai4	NP_001106504.1	WD40	359..782	CDD:225201	80/457 (18%)
		WD40	431..768	CDD:295369	74/431 (17%)
		WD40 repeat	435..480	CDD:293791	6/44 (14%)
		WD40 repeat	487..523	CDD:293791	6/38 (16%)
		WD40 repeat	613..650	CDD:293791	6/43 (14%)
		WD40 repeat	656..693	CDD:293791	9/37 (24%)
		WD40 repeat	698..736	CDD:293791	10/39 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910