Protein Alignment CG7099 and tftc-1

DIOPT Version :10

• Sequence 1: NP_609648.1
• Gene: CG7099 / 34753
• FlyBaseID: FBgn0032517
• Length: 1906
• Species: Drosophila melanogaster
• Sequence 2: NP_001294528.1
• Gene: tftc-1 / 177024
• WormBaseID: WBGene00021423
• Length: 1371
• Species: Caenorhabditis elegans
• Alignment Length: 1189
• Identity: 229/1189 - (19%)
• Similarity: 409/1189 - (34%)
• Gaps: 388/1189 - (32%)

  Fly   370 PEEEVFRAVARFGKRGLNSNELCHYTGINAT-------YMRHFVKRVKKH-GLVKEYSEQVGKSR 426
            |.:.:...:...|..||...||....|.::|       .....||...:| ..:.::.:..||.|
 Worm   106 PTDVILNTIRTGGTEGLGRAELGKTVGYDSTNKSGGRRVSDWIVKCTTEHPDHIGQFQKMNGKVR 170

  Fly   427 QFRFVAVGHLGDLSKEDEIKKKALEIRCKDEPNITESTDVLLKDLPEIVTNARP------IAF-- 483
            ..|:        ..|::|            :|   |..:.|.::..::.....|      |.|
 Worm   171 TIRY--------FWKQNE------------QP---ERFEKLFEEFQQLTACQCPFKIGEVIKFPE 212

  Fly   484 -KIKKTRAANQTQRQINRQKMIVRQIDQNCLVSLPRVLRSVQETERQAGFKDSLCRRSLMRLLRP 547
             |:...|.::.|.::.||...:|.|.  ..:|::.|:::::.|.|...|:|..:.::|:|:.|..
 Worm   213 KKLNTLRVSDVTLKRFNRIIALVNQF--RVIVTISRLIKTICEQEMADGYKFQIDKKSVMKCLLA 275

  Fly   548 MVEENIINVFEITLH----------------------------------YNQRVRVYRFATH--- 575
            :..:..:.:|:.|:.                                  :::..||:....|
 Worm   276 LQTKGFVRLFDTTVRSDNINHQIQIICHGSIDNVKNVEIIAGIEEMIDSFHKEGRVFPHGQHRTL 340

  Fly   576 ---------PKI---------GLDHAVMKREIV---------------KLKSNFH---------- 597
                     ||:         .:|..:.:...:               ..::|||
 Worm   341 KKHNQIEENPKVADEFNEKLENVDEDLTRNRTIHDRYQFFRLQTLRNSHKENNFHETDEFNGGNS 405

  Fly   598 -----LITEER------------------------MKRPSQMAPKERKEVLARRKLAPERSNAVF 633
                 .|.:|:                        .|.|:...|..:   |...:....|.:..:
 Worm   406 TLDDSQIEDEKTINLDEEGAENGEEDPDQAMINLFAKNPTVTTPASK---LRSNQFYFGRDSLGY 467

  Fly   634 KTQAPKLLLARTLHEFLY-YLH-HELSPEQKPLPMSAELVQQWQKSEPALQPRQFFDEWQA-DET 695
            :.:..:|::   |||.:| ::| |.:...    |.:.:|.       |..||   :..|:. |::
 Worm   468 QNKTVRLMI---LHEMIYNFVHGHPIDTS----PTAFDLF-------PPTQP---YRSWEVRDDS 515

  Fly   696 KVQPYTEDIGWRTFIPPLPRYVDKPSGWLYFMDAMDRMPLSLFMRICRIEREANDDLRL-QLQHP 759
            ....|.|:.....|:||.|:|.....||...:|.:..:|||:|:....:....:..|.| .|..|
 Worm   516 NAYVYLEEESPYRFMPPQPQYDGVDRGWFMTLDLLAALPLSVFVLTNYVPNTIDRPLLLTYLNDP 580

  Fly   760 IRQHYLLSQL---------KLETIVPRLKLQQIYVGTLRLLNNMGLIQVSEQKLG-RDSLHRW-- 812
            :::|..:..|         |.:.||.:|:...:.:..:||           ..:| ..|:.|:
 Worm   581 VKRHLCIGYLPDSIRDPIMKNKKIVKQLQHSFLCLAGMRL-----------AAVGPNPSVKRFPG 634

  Fly   813 -----VFLNQRTSLLDTTSSTEHNYMQVS---ADRSYTKLNFEFSSVEQLGNYWAKLQHICIYTK 869
                 .::.:|..|.||::|.: .|..|:   .:..|.|..:|.::...:..||..|:.|...|.
 Worm   635 ATSEMYYVARRVHLYDTSTSAK-GYACVNPSIEEGEYVKYEYELATRHDIIMYWHHLRAIVQSTP 698

  Fly   870 LGYRKSLSTQRILPARLKVLVFQPTV-EFD-QAVELDNGT--------VPGDHLGAAGLSSHLFA 924
            |.||......|....|.:    |.|: .|| :.||:|..|        |..|  |.||..:.||.
 Worm   699 LTYRIDDIGDRKFTQRHR----QYTIGVFDRKLVEVDYITGIEELYPKVAAD--GVAGFDAGLFV 757

  Fly   925 HQFRHW----------SW-VQRQNGGKSNAAR--EKAKRTVRK----------------RAVITR 960
            |..|||          || :||.....::..|  |:..::|.|                |.....
 Worm   758 HLKRHWDLITVPHGTVSWFIQRFRKCSTDCKRIVEQRVKSVHKDWNNFSRLSLADSDIVRTSSNP 822

  Fly   961 LKI--------GPRLAVRKARELSTGKTLKKSSGPR--DDIDRDALRNMRTLRVKWAPEEDRLLK 1015
            ||:        |...|.:..|  :|.||.::....|  |.:|..:.....::|.::.|:|...|.
 Worm   823 LKVEYPPIKKFGGTNAPKSNR--NTQKTARQIPKKRKLDSVDIVSSSARVSVRCRFTPKERDQLI 885

  Fly  1016 MGRAVYMFIDA-------PTMTLALCDLAVVCRDLIRRWLGIC-NKTTQ---AC-------VRRV 1062
            |.|||..|::.       ||          |.|||:..::... |||.|   ||       ..|:
 Worm   886 MIRAVGFFLNPVYRFWLDPT----------VLRDLMHEFVPESRNKTVQSLMACGVRELVRANRL 940

  Fly  1063 QFMVKMKRDIPDVPSWIYAMQTQPQFNTVYNERFLSQLKRDYPNKTDFQNALMTHFALMMAKLQR 1127
            .::.::.|::...||.:.     .|.|....|:.|.|:..                |::.:.||.
 Worm   941 AYLQRVVRNLSTFPSVLV-----HQMNAGQPEKILDQIPP----------------AVLQSVLQS 984

  Fly  1128 MIAKSQGSVSRQFLL---------------------------PDTLEAFGSQLRECRSAHEEQQL 1165
            :  ::.|.|||...|                           .:.:|..|..|.:.......||.
 Worm   985 L--RTDGLVSRSRTLEVVTELANKKDATLSFYFRHFFYHRFHSNLIEGVGRLLDKINDTATAQQQ 1047

  Fly  1166 LFQDPASETDLQVAVAHGVLHSNICCAKDKTLLNLQTFEIYKHFSEEVLNSAFNKARADSLLVAV 1230
            | |...:|.|     ..|   ..|..|..|.....:.|::.....::.:...|:....:.:::..
 Worm  1048 L-QTTTNELD-----GDG---PEIVIAAAKAFHPTEKFDLEMSVDDDEILKVFDIQEQEQIVMKK 1103

  Fly  1231 KRRNIQSAASRQISGPGHLLSSKYKYRLIYTKLT---HFLYD----------CFFALDQKLRADQ 1282
            .|               ||.:|...:..|:..|.   .|..|          |.| |.|..|
 Worm  1104 IR---------------HLENSDLHFERIHVNLAKKERFFDDVQSDEKLAEICDF-LSQNCR--- 1149

  Fly  1283 EQQLSSPHFGQLLVMGEWL 1301
             :..:||.    ..:.||:
 Worm  1150 -EISNSPR----ATLDEWI 1163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7099	NP_609648.1	B-block_TFIIIC	173..249	CDD:367858
tftc-1	NP_001294528.1	Tau138_eWH	221..310	CDD:320085	16/90 (18%)