Protein Alignment Ing5 and ing5a

DIOPT Version :9

• Sequence 1: NP_609647.1
• Gene: Ing5 / 34752
• FlyBaseID: FBgn0032516
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001093519.1
• Gene: ing5a / 792168
• ZFINID: ZDB-GENE-031016-1
• Length: 242
• Species: Danio rerio
• Alignment Length: 285
• Identity: 146/285 - (51%)
• Similarity: 183/285 - (64%)
• Gaps: 43/285 - (15%)

  Fly     1 MSSAIYLENYLDGLESLPTELERNFKLMRKLDDRAQTAMKSIDSHAKDFMRKLGENGAMSEDERR 65
            |::|||||:|||.:|:||.||:|||.|||:||:||:.....||..|::::..:..   ::.|:|.
Zfish     1 MATAIYLEHYLDSIENLPCELQRNFTLMRELDNRAEEKKCEIDKLAEEYIANVRN---LAPDQRV 62

  Fly    66 ERQEDIKALFGKAKEYSDDKVQLAIQTYELVDKQIRRLDNDLARFEGEIQEKASSTRAKSEEVVA 130
            |..:.|:..|.|.|||||||||||:||||:|||.|||||.||||||.|::||...:..:|
Zfish    63 EHLQKIQNGFSKCKEYSDDKVQLAMQTYEMVDKHIRRLDADLARFENELKEKLDVSGYES----- 122

  Fly   131 KKGRKKTKDSKTTGKKKKSASSDEETGRGNNQSNANSSVNSSSNAGQGSKKKKSKVNQEKETRKG 195
                   .|::|..|         .|||||.:......       |:|.|....:..::|:
Zfish   123 -------PDNRTHKK---------VTGRGNLKEKRRPK-------GRGRKSSDDESPRKKK---- 160

  Fly   196 GAQKKTVEVDDSEKESCHTAATHPSDVMDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 260
              .|.:.|..:|      ....|||||:|||||||||||||||||||||||||||||||||||||
Zfish   161 --MKNSPEFPES------ILPVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPIEWFHF 217

  Fly   261 ACVGLTTKPKGKWFCPKCTQDRKKK 285
            |||.||||||||||||:||||||||
Zfish   218 ACVDLTTKPKGKWFCPRCTQDRKKK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ing5	NP_609647.1	TNG2	1..278	CDD:227367	138/276 (50%)
		ING	6..108	CDD:289749	54/101 (53%)
		PHD_ING4_5	234..278	CDD:277061	42/43 (98%)
ing5a	NP_001093519.1	TNG2	1..235	CDD:227367	138/276 (50%)
		ING	6..105	CDD:289749	54/101 (53%)
		PHD_ING5	190..238	CDD:277155	45/47 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589776
Domainoid	1	1.000	163	1.000	Domainoid score	I3927
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	270	1.000	Inparanoid score	I2981
OMA	1	1.010	-	-		QHG55959
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	1	1.000	-	-		otm26500
orthoMCL	1	0.900	-	-		OOG6_101415
Panther	1	1.100	-	-	O	PTHR10333
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800