DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ing5 and bip2

DIOPT Version :9

Sequence 1:	NP_609647.1	Gene:	Ing5 / 34752	FlyBaseID:	FBgn0032516	Length:	285	Species:	Drosophila melanogaster
Sequence 2:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster

Alignment Length:	384	Identity:	81/384 - (21%)
Similarity:	127/384 - (33%)	Gaps:	116/384 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 NYLD------GLESLPTELERNFKLMRKLDDRAQTAMKSIDSHAKDFMRKLGENGAMS-EDERRE 66
            ||.|      ||.||..::.::.|.::|:.:......|    ..||..:|..:.|..| :.:|:.
  Fly  1026 NYEDITITPTGLTSLEPKMRKHHKKLKKVKEGKNKKKK----EKKDKSKKADQIGLPSFKSDRKI 1086

  Fly    67 RQEDIKALFGKAKEYSD-------------DKVQLA-------------------IQTYELVDKQ 99
            :..|.:....|.|:...             |||.||                   ..|..:...|
  Fly  1087 KANDKRQKKEKKKDKDKQILVHIPDDTEEFDKVPLANNDEPVLKSSSMTINPSLGAATSGISPNQ 1151

  Fly   100 IRRLDNDLA----RFEGEIQEKASSTRAKSEEVVAKKGRKKTKDSK---------TTGKKKKSAS 151
            |.:|...|:    .|....:|...:.:.|...:::.:.:|:.:|:.         .||..|...|
  Fly  1152 IPKLTLKLSGKSTLFSSSEKEMTDAGKLKQTTILSSENKKRERDNSPELARFSPLVTGPPKNKQS 1216

  Fly   152 SDEETGRGNNQ----------------------------SNANSSVNSSSNAGQGSKKKKSKV-- 186
            .....|..:..                            ||.|:|..:||.....|.....::
  Fly  1217 ETLHLGNSSTAVLPVPSPVAVRAVQLPVSQTSSNSAGWLSNPNNSNTASSTLSASSVLLPQQLML 1281

  Fly   187 --------------NQEKETRKGGAQKKTVEVDDSEKESCHTA-ATHPSDVMDMPVDPNEPTYC- 235
                          |......|.|.........:....:...| ::.||..:|  .:.|....|
  Fly  1282 APHTIMNNFVPAMCNSTGTVSKSGLCSSPPNTSEENANAMQIAESSRPSSYVD--AEGNRIWICP 1344

  Fly   236 LCHQVSYGE-MIGCDNPDCPIEWFHFACVGLTTKPKGK--WFCPKC-TQDR-----KKK 285
            .|.:|..|. |||||..|.   |:|:.|||:|..||..  |||..| |:.|     |||
  Fly  1345 ACGKVDDGSAMIGCDGCDA---WYHWICVGITFAPKDNDDWFCRVCVTKKRIHGSEKKK 1400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ing5	NP_609647.1	TNG2	1..278	CDD:227367	75/369 (20%)
		ING	6..108	CDD:289749	28/137 (20%)
		PHD_ING4_5	234..278	CDD:277061	21/47 (45%)
bip2	NP_651923.2	BTP	4..80	CDD:128846
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997	21/47 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900