Protein Alignment Ing5 and ING1

DIOPT Version :9

• Sequence 1: NP_609647.1
• Gene: Ing5 / 34752
• FlyBaseID: FBgn0032516
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_005528.4
• Gene: ING1 / 3621
• HGNCID: 6062
• Length: 422
• Species: Homo sapiens
• Alignment Length: 248
• Identity: 87/248 - (35%)
• Similarity: 138/248 - (55%)
• Gaps: 35/248 - (14%)

  Fly    39 MKSIDSHAKDFMRKLGENGAMSEDERRERQEDIKALFGKAKEYSDDKVQLAIQTYELVDKQIRRL 103
            :|.:|...:.|.|:  .:||    ::|.....::....:::|..|:|:|:..|..|||:.:.|::
Human   191 LKELDECYERFSRE--TDGA----QKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQV 249

  Fly   104 DNDLARFEGEIQEKASSTRAKSEEVVA--KKGRKKTKDSKTTGKKKKSASSDEETGRGNNQSNAN 166
            |:.:..||.  |::...|...|.:..|  .||....:..|...|:.:...::|      |:.||:
Human   250 DSHVELFEA--QQELGDTAGNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNE------NRENAS 306

  Fly   167 SSVNSSSNAGQGSKKKKSKVNQEKETRKGGAQKKTVEVDDSEKESCHTAATHPSDVMDMPVDPNE 231
            |:.:....|....|:||:|.:::|:..|..|:::                   :...|:|:||||
Human   307 SNHDHDDGASGTPKEKKAKTSKKKKRSKAKAERE-------------------ASPADLPIDPNE 352

  Fly   232 PTYCLCHQVSYGEMIGCDNPDCPIEWFHFACVGLTTKPKGKWFCPKCTQDRKK 284
            ||||||:||||||||||||.:||||||||:||||..||||||:||||..:.:|
Human   353 PTYCLCNQVSYGEMIGCDNDECPIEWFHFSCVGLNHKPKGKWYCPKCRGENEK 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ing5	NP_609647.1	TNG2	1..278	CDD:227367	84/240 (35%)
		ING	6..108	CDD:289749	17/68 (25%)
		PHD_ING4_5	234..278	CDD:277061	36/43 (84%)
ING1	NP_005528.4	ING	<189..254	CDD:289749	17/68 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	261..349		22/112 (20%)
		PHD_ING1_2	355..399	CDD:277059	36/43 (84%)
		PBR. /evidence=ECO:0000250|UniProtKB:Q9H160	405..422		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1434088at2759
OrthoFinder	1	1.000	-	-		FOG0000296
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2364
SonicParanoid	1	1.000	-	-		X195
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850