Protein Alignment RAB41 and Rab5

DIOPT Version :10

• Sequence 1: XP_011529250.1
• Gene: RAB41 / 347517
• HGNCID: 18293
• Length: 239
• Species: Homo sapiens
• Sequence 2: NP_523457.1
• Gene: Rab5 / 33418
• FlyBaseID: FBgn0014010
• Length: 219
• Species: Drosophila melanogaster
• Alignment Length: 195
• Identity: 77/195 - (39%)
• Similarity: 118/195 - (60%)
• Gaps: 10/195 - (5%)

Human    14 GGFGLEAAER---TEYQSLCKSKLLFLGEQSVGKTSIISRFMYNSFGCACQATVGIDFLSKTMYL 75
            |..|...|:|   |.....|:.||:.|||.:|||:|::.||:...|....::|:|..||::|:.:
  Fly     9 GASGTGTAQRPNGTSQNKSCQFKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQTICI 73

Human    76 EDQIVQLQLWDTAGQERFHSLIPSYIRDSTIAVVVYDITNINSFKETDKWVEHVRAERGDDVVIM 140
            ||.:|:.::||||||||:|||.|.|.|.:..|:|||||.|.:||:....||:.:..:...::||.
  Fly    74 EDTVVKFEIWDTAGQERYHSLAPMYYRGAQAAIVVYDIQNQDSFQRAKTWVKELHKQASPNIVIA 138

Human   141 LLGNKIDLDNKRQVTAEQGEEKSRNLNVMFIETSAKTGYNVKKLFRRVASALLSTRTSPPPKEGS 205
            |.|||.||.|.|.|..::.::.:....::|:|||||||.||..:|..:|..|       |..:|:
  Fly   139 LAGNKADLSNIRVVEFDEAKQYAEENGLLFMETSAKTGMNVNDIFLAIAKKL-------PKNDGA 196

Human   206  205
              Fly   197  196

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB41	XP_011529250.1	Rab6	33..192	CDD:206654	68/158 (43%)
Rab5	NP_523457.1	Rab5_related	29..191	CDD:206653	69/168 (41%)