DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DGAT2L6 and CG1941

DIOPT Version :9

Sequence 1:	NP_940914.1	Gene:	DGAT2L6 / 347516	HGNCID:	23250	Length:	337	Species:	Homo sapiens
Sequence 2:	NP_001286161.1	Gene:	CG1941 / 35718	FlyBaseID:	FBgn0033214	Length:	352	Species:	Drosophila melanogaster

Alignment Length:	352	Identity:	134/352 - (38%)
Similarity:	196/352 - (55%)	Gaps:	45/352 - (12%)

- Green bases have known domain annotations that are detailed below.

Human    19 LQWIPVYIFLG------AIPILLIPYFLLF--SKFWPLAVL---SLAW-------LTYDW----N 61
            ::|.|..:.:.      |:..|::.:.:|.  |.|:..|||   ||.|       |.|.:    .
  Fly     3 IEWAPKGVPMERRRQTFAMAFLILSFMILSFGSYFFVAAVLFYGSLLWRTIMVIYLVYVYANHKR 67

Human    62 THS-QGGRRSAWV---RNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFAT 122
            ||| ..|  :.|.   .|| |::::|:||||:||||.:|.|..|||:|:.|||||..|:.||...
  Fly    68 THSIMDG--NGWKINRNNW-LFRHYRDYFPVQLVKTAELPPNKNYILASFPHGILGTGISINMGL 129

Human   123 EATGIARIFPSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKG-----------S 176
            :.:...::||.:.|.|.||::.|..||||..:.|.|:..||..||.||||:..           :
  Fly   130 DISKWLQLFPQVRPKVATLDQNFLTPIVRGLLRSWGLVSVSKEALVYLLTKSNDPKHKDNRDGFT 194

Human   177 GNAVVIVVGGAAEALLCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTW 241
            .|||.|:||||.|||...||...|.||.||||||||::||:.:||::||||.::.:|...|..:.
  Fly   195 SNAVAILVGGAQEALDSHPGKYILTLKNRKGFVKMAIRTGSSIVPTFSFGEVDILDQVANPPNSR 259

Human   242 LRLFQKTFQDTFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQKTVDK 306
            :|    .|||..|:|.|::.....|||....|:||||..|.|..|||.|:.:.:..:|:...|||
  Fly   260 VR----RFQDFVKRITGISPLIPVGRGIFNYSFGFLPNRRRIVQVVGAPIDVVQSDQPDAAYVDK 320

Human   307 YHALYISALRKLFDQHKVEYGLPETQE 333
            .|...|..|.|:|.::|.:| :|.:::
  Fly   321 IHKQVIDDLEKMFAKYKDQY-IPNSKQ 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DGAT2L6	NP_940914.1	LPLAT	38..336	CDD:302626	130/327 (40%)
CG1941	NP_001286161.1	LPLAT	50..340	CDD:302626	120/296 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146789
Domainoid	1	1.000	214	1.000	Domainoid score	I2726
eggNOG	1	0.900	-	-		E1_KOG0831
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	235	1.000	Inparanoid score	I3400
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53531
OrthoDB	1	1.010	-	-		D1347007at2759
OrthoFinder	1	1.000	-	-		FOG0000289
OrthoInspector	1	1.000	-	-		mtm8637
orthoMCL	1	0.900	-	-		OOG6_100399
Panther	1	1.100	-	-	O	PTHR12317
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X186
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.770