Protein Alignment loqs and STAU1

DIOPT Version :10

• Sequence 1: NP_609646.1
• Gene: loqs / 34751
• FlyBaseID: FBgn0032515
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_001309861.1
• Gene: STAU1 / 6780
• HGNCID: 11370
• Length: 583
• Species: Homo sapiens
• Alignment Length: 591
• Identity: 128/591 - (21%)
• Similarity: 199/591 - (33%)
• Gaps: 187/591 - (31%)

  Fly     8 GSSLPQQLQNLHIQPQQASPN------------PVQTG--------------------------- 33
            ||.:..:.|:|..||..:.|:            |:|..
Human    17 GSQILNKNQSLLSQPLMSIPSTTSSLPSENAGRPIQNSALPSASITSTSAAAESITPTVELNALC 81

  Fly    34 --------FAPRRHYNNLVGLGNGNAVSGS-------PVKGAPLGQRHVKLKKEKISAQVAQLSQ 83
                    :.|...|:.:....|.|...|:       |....||      |.:.::|....|.:.
Human    82 MKLGKKPMYKPVDPYSRMQSTYNYNMRGGAYPPRYFYPFPVPPL------LYQVELSVGGQQFNG 140

  Fly    84 PGQLQLSDVGDPALAGGSGLQGGVGLMGVILPSDEALKFVSETDANGLAMKTPVSILQELLSRRG 148
            .|:.:.:...|.|......||..        |..|.|:............|:.:|.:.|:..:|.
Human   141 KGKTRQAAKHDAAAKALRILQNE--------PLPERLEVNGRESEEENLNKSEISQVFEIALKRN 197

  Fly   149 ITPGYE---LVQI---EGAIHEPTFRFRVSFKDKDTPFTAMGAGRSKKEAKHAAARALIDKLIGA 207
            :...:|   |.|:   .|..|...|..:||..:    |...|.|:|||.:|..||.|::::|  .
Human   198 LPVNFESFPLKQVARESGPPHMKNFVTKVSVGE----FVGEGEGKSKKISKKNAAIAVLEEL--K 256

  Fly   208 QLPESPS-SSAGPSVTGLT-------VAGSGGDGNANATGGGDASDKTVGNPIGWLQEMCMQRRW 264
            :||..|: ....|.:...|       .:...|.|.               |||..|.::...::.
Human   257 KLPPLPAVERVKPRIKKKTKPIVKPQTSPEYGQGI---------------NPISRLAQIQQAKKE 306

  Fly   265 PPPSYETETEVGLPHERLFTIACSILNYREMGKGKSKKIAKRLAAHRMWMRL------------- 316
            ..|.|...||.|||..|.|.:...:.|:...|.|.:||:|||.||..|...|
Human   307 KEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLEILGFKVPQAQPTKPA 371

  Fly   317 ----QETPI----DSGKISDSICGELEGEPRSSENYYGELKDISVPTLTTQ-------------- 359
                ::|||    |..|::....|  .|:...:.|...|.:   :|.|:.|
Human   372 LKSEEKTPIKKPGDGRKVTFFEPG--SGDENGTSNKEDEFR---MPYLSHQQLPAGILPMVPEVA 431

  Fly   360 HSNKVSQFHKTLKNAT---------------GKKLL-----KLQKTCLKNN-------------- 390
            .:..|||.|.| |:.|               .::||     ...:|.||||
Human   432 QAVGVSQGHHT-KDFTRAAPNPAKATVTAMIARELLYGGTSPTAETILKNNISSGHVPHGPLTRP 495

  Fly   391 --KIDYIKLLGEIATENQFEVTYVDIEEKTFSGQFQCLVQLSTLPVGVCHGSGPTAADAQRHAAQ 453
              ::||:..:      ..|:|.|.|. .|....:|..|:..|:.|..:.||.|.........||.
Human   496 SEQLDYLSRV------QGFQVEYKDF-PKNNKNEFVSLINCSSQPPLISHGIGKDVESCHDMAAL 553

  Fly   454 NALEYL 459
            |.|:.|
Human   554 NILKLL 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
loqs	NP_609646.1	DSRM_PRKRA-like_rpt1	134..206	CDD:380691	23/77 (30%)
		DSRM_PRKRA-like_rpt2	250..316	CDD:380692	24/65 (37%)
		DSRM_PRKRA-like_rpt3	393..463	CDD:380693	19/67 (28%)
STAU1	NP_001309861.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	34..55		3/20 (15%)
		DSRM_STAU1_rpt2	82..146	CDD:380710	12/69 (17%)
		DSRM_SF	183..255	CDD:444671	22/75 (29%)
		DSRM_STAU1_rpt4	282..367	CDD:380714	27/99 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	366..403		7/38 (18%)
		Staufen_C	454..563	CDD:465131	26/113 (23%)