DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment loqs and zfr2

DIOPT Version :9

Sequence 1:	NP_609646.1	Gene:	loqs / 34751	FlyBaseID:	FBgn0032515	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	XP_005161660.1	Gene:	zfr2 / 567465	ZFINID:	ZDB-GENE-070705-184	Length:	1004	Species:	Danio rerio

Alignment Length:	435	Identity:	87/435 - (20%)
Similarity:	129/435 - (29%)	Gaps:	187/435 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 PQQLQNLHIQPQQASPNPVQTGFAPRRHYNNLVGLGNGNAVSGSPV----------------KGA 60
            |||      |||...|.|.||...|::..|:......|::||...|                ||.
Zfish   248 PQQ------QPQPQPPPPQQTQQPPKQLANSSWSNSGGSSVSSPAVSSYRKPAFHQNKIQKPKGP 306

  Fly    61 PL-------------------------GQRHVKLK-KEKISAQVAQLSQPGQLQL-------SDV 92
            |.                         ||:|.|.: .:|..:||....:..|.||       |..
Zfish   307 PKQPQLHYCDICKISCAGPQTYREHLEGQKHKKKEAAQKSGSQVTNGPRGVQTQLRCELCDVSCT 371

  Fly    93 GDPALAG---GSGLQGGVGL---MGVILPSDEALKFVSETDANGLAMKTPVSILQELLSRRGITP 151
            |..|.|.   ||..|..|.|   :|..:||.|.: .||.|.|   ||.|..|
Zfish   372 GADAYAAHIRGSKHQKVVKLHTKLGKPIPSTEPV-LVSSTPA---AMTTTTS------------- 419

  Fly   152 GYELVQIEGAIHEPTFRFRVSFKDKDTPFTAMGAGRSKKEAKHAAARALIDKLIGAQLPESPSSS 216
                              :.:.....||.:|....::....|.|||..       .:.|.:.|::
Zfish   420 ------------------KPAASTSSTPTSAAQKIQTAAPPKPAAAPV-------KKPPPAVSAA 459

  Fly   217 AGPSVTG-----------------LTVAGSGGDGNANATG-GGDASDKTVGNPIG--WLQE---- 257
            ..|:|..                 :....|..|.:|:||| .||.      .|:|  :::|
Zfish   460 KAPAVVSKPSTSTVVKMEEVKPPVVKTDPSSDDEDADATGPQGDI------QPVGHDYVEEVRND 518

  Fly   258 -----------------------MCMQRRWPPPSYETETEVGLPHE--------RLFTIACSILN 291
                                   |.::.|.....|:.:....||.|        :|..:
Zfish   519 DGKVIRFHCKLCECSFNDPNAKDMHLKGRRHRLQYKKKVNPDLPVEIKPSNRARKLLEV------ 577

  Fly   292 YREMGKGKSKKIAKRLAAHRM---------------WMRLQETPI 321
              ::.|.|.|.:.||......               |.|::|..:
Zfish   578 --KLRKQKQKSVLKRQQEDEQRWHMEMSRRYEEDMYWRRMEEEQV 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
loqs	NP_609646.1	DSRM	136..204	CDD:214634	8/67 (12%)
		DSRM	250..316	CDD:238007	16/117 (14%)
		DSRM	394..460	CDD:214634
zfr2	XP_005161660.1	ZnF_U1	313..342	CDD:197732	4/28 (14%)
		C2H2 Zn finger	315..337	CDD:275371	2/21 (10%)
		ZnF_U1	358..392	CDD:197732	11/33 (33%)
		C2H2 Zn finger	363..385	CDD:275371	6/21 (29%)
		ZnF_U1	524..555	CDD:197732	3/30 (10%)
		C2H2 Zn finger	527..549	CDD:275371	2/21 (10%)
		DZF	718..968	CDD:128842
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594017
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930