DRSC/TRiP Functional Genomics Resources

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Protein Alignment loqs and ZFR

DIOPT Version :9

Sequence 1:NP_609646.1 Gene:loqs / 34751 FlyBaseID:FBgn0032515 Length:465 Species:Drosophila melanogaster
Sequence 2:NP_057191.2 Gene:ZFR / 51663 HGNCID:17277 Length:1074 Species:Homo sapiens


Alignment Length:364 Identity:71/364 - (19%)
Similarity:120/364 - (32%) Gaps:127/364 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 QRHVKLKKEKISAQVAQLSQPGQLQLSDVGDPALAGGSGLQGGVGLMGVILPSDEALKFV---SE 125
            :|.:||..:.:|......::.|..:.....|.||.|  .|:.||...|::|..|..:..|   ||
Human   752 ERALKLVSDSLSEHEKNKNKEGDDKKEGGKDRALKG--VLRVGVLAKGLLLRGDRNVNLVLLCSE 814

  Fly   126 TDANGLAMKTPVSILQELLSRRGITPGYELVQIEGAIH----------EPTFRFRVSFKD----- 175
            ..:     ||.:|.:.|.|.::......|...|:.|:.          ||..:..::...     
Human   815 KPS-----KTLLSRIAENLPKQLAVISPEKYDIKCAVSEAAIILNSCVEPKMQVTITLTSPIIRE 874

  Fly   176 -------------KDTPFT-----AMGAGRSKKEAKHAAARA----------------------- 199
                         ||.|..     .:.|..:.:.||...|||                       
Human   875 ENMREGDVTSGMVKDPPDVLDRQKCLDALAALRHAKWFQARANGLQSCVIIIRILRDLCQRVPTW 939

  Fly   200 ----------LIDKLI-GAQLPESPSSSAGPSV--------TGLTVAGSGGDGNANATGGGDASD 245
                      |::|.| .|..|:||    |.::        :|:.:.||.|           ..|
Human   940 SDFPSWAMELLVEKAISSASSPQSP----GDALRRVFECISSGIILKGSPG-----------LLD 989

  Fly   246 KTVGNPIGWLQEMCMQRRWPPPSYETETEVGLPHERLFTIACSILNYRE----MGKGKSKKIAKR 306
            ....:|...|..|..|:|      |..|...       ..|..:|.:|:    :|.....::::|
Human   990 PCEKDPFDTLATMTDQQR------EDITSSA-------QFALRLLAFRQIHKVLGMDPLPQMSQR 1041

  Fly   307 LAAHRMWMRLQETPIDSGKISDSICG-ELEGEPRSSENY 344
            ...|....|.::        ||.:.| |.||: :..::|
Human  1042 FNIHNNRKRRRD--------SDGVDGFEAEGK-KDKKDY 1071

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
loqsNP_609646.1 DSRM 136..204 CDD:214634 18/133 (14%)
DSRM 250..316 CDD:238007 13/69 (19%)
DSRM 394..460 CDD:214634
ZFRNP_057191.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 120..139
ZnF_U1 331..360 CDD:197732
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 349..377
ZnF_U1 384..413 CDD:197732
Epiglycanin_TR 420..477 CDD:283334
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 421..447
ZnF_U1 581..612 CDD:197732
C2H2 Zn finger 584..606 CDD:275371
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 702..723
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 761..781 2/19 (11%)
DZF 784..1038 CDD:128842 55/288 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1040..1074 10/41 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165158159
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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